This Review compiles the evolution, mechanistic understanding, and more recent advances
in enantioselective Pd-catalyzed allylic substitution and decarboxylative and oxidative allylic …

In chemistry, a nucleophile is a molecule or ion with a lone pair of electrons. It donates both
bonding electrons to its reaction partner (the electrophile) when forming a chemical bond. 1 …

Branched allylic esters and carboxylates are fundamental motifs prevalent in natural
products and drug molecules. The direct allylic C–H oxygenation of internal alkenes …

Hydroxylation of aryl carbon–hydrogen bonds with transition metal catalysts has proven
challenging when oxygen is used as the oxidant. Here, we report a palladium complex …

Catalytic oxidation is a key technology for converting petroleum-based feedstocks to useful
chemicals of a high oxidation state such as alcohols, carbonyl compounds, and epoxides …

In organic molecules carboxylic acid groups are among the most common functionalities.
Activated derivatives of carboxylic acids have long served as versatile connection points in …

The transformation of unsaturated hydrocarbons through the action of metal complexes
continues to constitute a very important field of organometallic chemistry, particularly when …

The development of mild, general, and selective transition metal catalyzed methods for the
functionalization of carbon–hydrogen bonds represents a significant current challenge in …

Sulfoxide ligation to Pd (II) salts is shown to selectively promote C− H oxidation versus
Wacker oxidation chemistry and to control the regioselectivity in the C− H oxidation products …

Transition Metal Reagents and Catalysts Innovations in Organic Synthesis Jiro Tsuji
Emeritus Professor, Tokyo Institute of Technology, Japan Numerous innovative and practical …