Neuronal integration in Purkinje neurons involves many forms of Ca2+ signaling. Two
afferent synaptic inputs, the parallel and the climbing fibers, provide a major drive for these …

Abstract T-type Ca2+ channels (T channels) underlie rhythmic burst discharges during
neuronal oscillations that are typical during sleep. However, the Ca2+-dependent effectors …

T-type voltage-gated calcium channels are expressed in the dendrites of many neurons,
although their functional interactions with postsynaptic receptors and contributions to …

The orphan G lu D 2 receptor belongs to the ionotropic glutamate receptor family but does
not bind glutamate. Ligand‐gated G lu D 2 currents have never been evidenced, and …

Rapid, localised photolytic release of neurotransmitters from caged precursors at synaptic
regions in the extracellular space is greatly hampered at irradiation wavelengths in the near …

Acute alcohol consumption causes deficits in motor coordination and gait, suggesting an
involvement of cerebellar circuits, which play a role in the fine adjustment of movements and …

Consumption of alcoholic beverages produces alterations in motor coordination and
equilibrium that are responsible for millions of accidental deaths. Studies indicate that …

Photolysis is widely used in experimental neuroscience to isolate post-synaptic receptor
activation from presynaptic processes, to determine receptor mechanisms in situ, for …

Low threshold voltage-gated T-type calcium channels have long been implicated in the
electrical excitability and calcium signaling of cerebellar Purkinje neurons although the …

The cerebellum plays an important role in diverse brain functions, ranging from motor
learning to cognition. Recent studies have suggested that molecular and cellular …