There has been a long-standing need for guidelines on the diagnosis and treatment of
keloids and hypertrophic scars that are based on an understanding of the pathomechanisms …

Background: In 2010, this Journal published my comprehensive review of the literature on
hypertrophic scars and keloids. In that article, I presented evidence-based algorithms for the …

Keloids and hypertrophic scars are fibroproliferative disorders (FPDs) of the skin that result
from abnormal healing of injured or irritated skin. They can be called pathological or …

Background The high recurrence rate of keloids has lead to the use of multiple treatment
adjuncts to improve cosmetic outcomes after surgery. To date, there has been no single …

Background: Excision followed by adjuvant irradiation is considered safe and most
efficacious for treatment of keloid scars. Recently, different authors published successful …

Keloid scars, characterized by abnormal fibroproliferation and excessive extracellular matrix
(ECM) production that extends beyond the original wound, often cause pruritus, pain, and …

Keloids can be treated in a number of ways, including by surgery. Multiple studies now show
that while surgical monotherapy associates with extremely high rates of recurrence (50 …

Objective: Radiation therapy combined with surgical excision was considered as one of the
most effective treatment plans for keloid lesions. However, there was no unanimity found …

Background: The ear is a common site for keloid formation, usually after trauma or ear
piercing. This study is a meta-analysis to identify effective treatments for ear keloids after …

Keloids (K) and hypertrophic scars (HS) are abnormal responses to wound healing that
occur as the result of dermal inflammation. Despite the advances on their treatment, many …