Synovial fibroblast gene expression is associated with sensory nerve growth and pain in rheumatoid arthritis
It has been presumed that rheumatoid arthritis (RA) joint pain is related to inflammation in
the synovium; however, recent studies reveal that pain scores in patients do not correlate …
the synovium; however, recent studies reveal that pain scores in patients do not correlate …
Machine learning identification of thresholds to discriminate osteoarthritis and rheumatoid arthritis synovial inflammation
Background We sought to identify features that distinguish osteoarthritis (OA) and
rheumatoid arthritis (RA) hematoxylin and eosin (H&E)-stained synovial tissue samples …
rheumatoid arthritis (RA) hematoxylin and eosin (H&E)-stained synovial tissue samples …
Computer vision analysis of rheumatoid arthritis synovium reveals lymphocytic inflammation is associated with immunoglobulin skewing in blood
D Frezza, E DiCarlo, C Hale, D Ramirez… - Arthritis & …, 2023 - Wiley Online Library
Objective We sought to develop computer vision methods to quantify aggregates of cells in
synovial tissue and compare these with clinical and gene expression parameters. Methods …
synovial tissue and compare these with clinical and gene expression parameters. Methods …
Automated multi-scale computational pathotyping (AMSCP) of inflamed synovial tissue
RD Bell, M Brendel, MA Konnaris, J Xiang… - Nature …, 2024 - nature.com
Rheumatoid arthritis (RA) is a complex immune-mediated inflammatory disorder in which
patients suffer from inflammatory-erosive arthritis. Recent advances on histopathology …
patients suffer from inflammatory-erosive arthritis. Recent advances on histopathology …
Machine Learning Reveals Synovial Fibroblast Genes Associated with Pain Affect Sensory Nerve Growth in Rheumatoid Arthritis
It has been presumed that rheumatoid arthritis (RA) joint pain is related to inflammation in
the synovium; however, recent studies reveal that pain scores in patients do not correlate …
the synovium; however, recent studies reveal that pain scores in patients do not correlate …
OP0223 DISTINGUISHING OSTEOARTHRITIS AND RHEUMATOID ARTHRITIS SYNOVIUM WITH MACHINE LEARNING USING AUTOMATED CELL DENSITY AND …
Background Joint damage in the knee can be severe in both rheumatoid arthritis (RA) and
osteoarthritis (OA) such that total knee replacement (TKR) is often the only management …
osteoarthritis (OA) such that total knee replacement (TKR) is often the only management …