Objective: The authors investigated the clinical outcomes of commonly used antidepressants
among older adults who initiated first-time antidepressants for depression by analyzing the 1 …

Objective: To examine changes in annual patterns of psychotropic medication use in
Australia from 2007 to 2015. Methods: We used a 10% sample of individual-level nationwide …

Objective: Both preclinical studies and clinical trials have indicated that the combination of a
selective serotonin reuptake inhibitor (SSRI) and a statin may have superior antidepressant …

Objective Concurrent polypharmacy and potentially-inappropriate-medication (PIMs) use
with antidepressants in older adults is understudied. We investigated the prevalence and …

Background Nonsteroidal anti‐inflammatory drugs (NSAID s) and paracetamol have been
shown to yield the potential of adjunctive antidepressant treatment effects to selective …

Aims/hypothesis We aimed to assess whether current antidepressant therapy or a history of
hospital-diagnosed depression affects diabetes treatment initiation, adherence, and HbA 1c …

Quasi-experiments are likely to be the workhorse study design used to generate evidence
about the comparative effectiveness of alternative treatments, because of their feasibility …

Aims: The purpose of this study was to describe how washout period duration affects the
size and accuracy of retrospective incident user cohorts. Materials & methods: MarketScan …

Abstract Background and Objective Antidepressant use in older adults (≥ 65 years) is
understudied in large population-based samples, particularly in recent years and regarding …

Background In 2003–2004 and 2007–2008, the regulatory banning of SSRI use in pediatrics
and young adults due to concerns regarding suicidality risk coincided with negative media …