Nano-emulgel is an emerging drug delivery system intended to enhance the therapeutic
profile of lipophilic drugs. Lipophilic formulations have a variety of limitations, which includes …

Glioblastoma multiforme (GBM) is abnormal cell proliferation of glial cells. GBM is the grade
IV glioma brain cancer which is life-threatening to many individuals affected by this cancer …

Brain, a subtle organ of multifarious nature presents plethora of physiological, metabolic and
bio-chemical convolutions that impede the delivery of biomolecules and thereby resulting in …

Temozolomide is a drug approved for treating glioblastomas, which has 100% oral
bioavailability but gets degraded at physiological pH thus having very short half-life and only …

The current study aimed to develop a topical emulgel of dasatinib (DTB) for rheumatoid
arthritis (RA) treatment to reduce systemic side effects. The quality by design (QbD) …

Delivering drugs to the brain has always been a challenging task due to the restrictive
properties of the blood-brain barrier (BBB). Intranasal delivery is therefore emerging as an …

Repaglinide (REP), an antidiabetic drug, is recently explored in ameliorating
neurodegenerative disorders (Huntington's and Alzheimer's disease) by targeting neuronal …

The interaction of temozolomide (TMZ)(the main chemotherapeutic agent for brain tumors)
with blood components has not been studied at the molecular level to date, even though …

The most common primary malignant brain tumors in adults are gliomas. Glioblastoma is the
most prevalent and aggressive tumor subtype of glioma. Current standards for the treatment …

Glioblastoma multiforme (GBM) is the most prevalent and aggressive type of brain cancer in
adults. Temozolomide (TMZ) is the chemotherapeutic agent used to treat primary central …