[HTML][HTML] Antibiotic resistance in microbes: History, mechanisms, therapeutic strategies and future prospects

TM Uddin, AJ Chakraborty, A Khusro… - Journal of infection and …, 2021 - Elsevier
Antibiotics have been used to cure bacterial infections for more than 70 years, and these low-
molecular-weight bioactive agents have also been used for a variety of other medicinal …

Mobile genetic elements associated with antimicrobial resistance

SR Partridge, SM Kwong, N Firth… - Clinical microbiology …, 2018 - Am Soc Microbiol
Strains of bacteria resistant to antibiotics, particularly those that are multiresistant, are an
increasing major health care problem around the world. It is now abundantly clear that both …

Using SPAdes de novo assembler

A Prjibelski, D Antipov, D Meleshko… - Current protocols in …, 2020 - Wiley Online Library
Abstract SPAdes—St. Petersburg genome Assembler—was originally developed for de
novo assembly of genome sequencing data produced for cultivated microbial isolates and …

Sequencing-based methods and resources to study antimicrobial resistance

M Boolchandani, AW D'Souza, G Dantas - Nature Reviews Genetics, 2019 - nature.com
Antimicrobial resistance extracts high morbidity, mortality and economic costs yearly by
rendering bacteria immune to antibiotics. Identifying and understanding antimicrobial …

Antibiotic resistance in Pseudomonas aeruginosa–Mechanisms, epidemiology and evolution

J Botelho, F Grosso, L Peixe - Drug resistance updates, 2019 - Elsevier
Antibiotics are powerful drugs used in the treatment of bacterial infections. The inappropriate
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …

PLSDB: advancing a comprehensive database of bacterial plasmids

GP Schmartz, A Hartung, P Hirsch, F Kern… - Nucleic Acids …, 2022 - academic.oup.com
Plasmids are known to contain genes encoding for virulence factors and antibiotic
resistance mechanisms. Their relevance in metagenomic data processing is steadily …

MOB-suite: software tools for clustering, reconstruction and typing of plasmids from draft assemblies

J Robertson, JHE Nash - Microbial genomics, 2018 - microbiologyresearch.org
Large-scale bacterial population genetics studies are now routine due to cost-effective
Illumina short-read sequencing. However, analysing plasmid content remains difficult due to …

Sequence and cultivation study of Muribaculaceae reveals novel species, host preference, and functional potential of this yet undescribed family

I Lagkouvardos, TR Lesker, TCA Hitch, EJC Gálvez… - Microbiome, 2019 - Springer
Background Bacteria within family S24-7 (phylum Bacteroidetes) are dominant in the mouse
gut microbiota and detected in the intestine of other animals. Because they had not been …

The global distribution and spread of the mobilized colistin resistance gene mcr-1

R Wang, L Van Dorp, LP Shaw, P Bradley… - Nature …, 2018 - nature.com
Colistin represents one of the few available drugs for treating infections caused by
carbapenem-resistant Enterobacteriaceae. As such, the recent plasmid-mediated spread of …

PlasFlow: predicting plasmid sequences in metagenomic data using genome signatures

PS Krawczyk, L Lipinski… - Nucleic acids research, 2018 - academic.oup.com
Plasmids are mobile genetics elements that play an important role in the environmental
adaptation of microorganisms. Although plasmids are usually analyzed in cultured …