Tissue engineering has emerged as a new treatment approach for bone repair and
regeneration seeking to address limitations associated with current therapies, such as …

Wounding and healing are archaic principles, prerequisite for survival of any biologic
material. However, strategies to cope with wounding may be quite different among …

Ankle fractures in patients with diabetes mellitus (DM) have long been recognized as a
challenge to practicing clinicians in terms of delays in fracture healing, difficulties with …

Background Type 1 diabetes mellitus (DM) has been shown to alter the properties of bone
and impair fracture healing in both humans and animals. The objective of this study was to …

Blood clots (haematomas) that form immediately following a bone fracture have been shown
to be vital for the subsequent healing process. During the clotting process, a number of …

This study aimed at investigating in vitro and in vivo the efficiency of commercially available
fibrin as a carrier for controlled and sustained bone morphogenetic protein-2 (BMP-2) …

Up to 20% of patients with total joint arthroplasty will develop radiographic evidence of
aseptic loosening (AL), which most likely results from an inflammatory response to billions of …

Insulin-dependent type 1 diabetes mellitus (IDDM) has been shown to alter the properties of
bone and impair bone repair in both humans and animals. The objective of this study was …

Purpose: To increase human bone graft regeneration and quality by the use of a mixture
containing autologous ground calvarial bone, human recombinant tissue factor (rhTF) …

Insulin-dependent type 1 diabetes mellitus (IDDM) has been shown to alter the properties of
bone and to impair fracture-healing in both humans and animals. The objective of this study …