Metalloporphyrins are widely used throughout the biosphere, and of these heme (iron
protoporphyrin IX, Figure 1) is one of the most abundant and widely used. Heme shuttles …

Heme-copper oxidases (HCOs) are terminal enzymes on the mitochondrial or bacterial
respiratory electron transport chain, which utilize a unique heterobinuclear active site to …

Cytochrome P450 enzymes are responsible for the phase I metabolism of approximately
75% of known pharmaceuticals. P450s perform this and other important biological functions …

Oxygen reduction reaction (ORR) is an important process involved in natural and artificial
energy conversion schemes. As inspired by cytochrome c oxidases (CcOs), which are …

The functionalization of C–H bonds has yet to achieve widespread use in synthetic
chemistry in part because of the lack of synthetic reagents that function in the presence of …

Recently, we reported the spectroscopic and kinetic characterizations of cytochrome P450
compound I in CYP119A1, effectively closing the catalytic cycle of cytochrome P450 …

Iron (III) meso-tetra (2-carboxyphenyl) porphine chloride (1) was investigated as a soluble
electrocatalyst for the oxygen reduction reaction (ORR) in acetonitrile with [H (DMF)+] OTf …

This review examines the monooxygenase, peroxidase and peroxygenase properties and
reaction mechanisms of cytochrome P450 (CYP) enzymes in bacterial, archaeal and …

Cytochrome P450 enzymes catalyze a broad diversity of reactions, including well-
established transformations such as carbon and nitrogen hydroxylation, heteroatom …

This review examines the monooxygenase, peroxidase, and peroxygenase properties of
cytochrome P450 (P450) 1 enzymes and their mechanisms of action in archaeal, bacterial …