Advances in the knowledge of the underlying airway remodeling mechanisms in chronic rhinosinusitis based on the endotypes: a review

K Lee, J Tai, SH Lee, TH Kim - International journal of molecular sciences, 2021 - mdpi.com
Chronic rhinosinusitis (CRS) is a chronic inflammatory condition of the nasal and paranasal
sinus mucosa that affects up to 10% of the population worldwide. CRS is the most …

The role of Staphylococcus aureus enterotoxin B in chronic rhinosinusitis with nasal polyposis

Z Chegini, M Didehdar, A Khoshbayan… - Cell Communication and …, 2022 - Springer
CRS with nasal polyps (CRSwNP) is a multifactorial disease, and various etiological factors
like bacterial superantigens are known to develop this disease. Recent studies reported that …

Protein stabilization of ITF2 by NF-κB prevents colitis-associated cancer development

M Lee, YS Kim, S Lim, SH Shin, I Kim, J Kim… - Nature …, 2023 - nature.com
Chronic colonic inflammation is a feature of cancer and is strongly associated with
tumorigenesis, but its underlying molecular mechanisms remain poorly understood …

Bone morphogenetic protein-2 as a novel biomarker for refractory chronic rhinosinusitis with nasal polyps

JY Kim, S Lim, HS Lim, YS Kim, KM Eun… - Journal of Allergy and …, 2021 - Elsevier
Background Bone morphogenetic proteins (BMPs), which are members of the TGF-β
superfamily, regulate bone remodeling by stimulating osteoblasts and osteoclasts. Although …

Identification of hub genes and immune cell infiltration characteristics in chronic rhinosinusitis with nasal polyps: Bioinformatics analysis and experimental validation

Y Pan, L Wu, S He, J Wu, T Wang… - Frontiers in Molecular …, 2022 - frontiersin.org
The aim of our study is to reveal the hub genes related to the pathogenesis of chronic
rhinosinusitis with nasal polyps (CRSwNP) and their association with immune cell infiltration …

[HTML][HTML] Crosstalk between mucosal inflammation and bone metabolism in chronic rhinosinusitis

R Khalmuratova, HW Shin - Clinical and Experimental …, 2021 - synapse.koreamed.org
Chronic rhinosinusitis (CRS) is a multifactorial and highly heterogeneous upper airway
disease that affects approximately 12% of the general population. There is increasing …

[HTML][HTML] Ginsenoside F1 attenuates eosinophilic inflammation in chronic rhinosinusitis by promoting NK cell function

SJ Kim, J Lee, WS Choi, HJ Kim, MY Kim… - Journal of Ginseng …, 2021 - Elsevier
Background Ginsenosides have beneficial effects on several airway inflammatory disorders
primarily through glucocorticosteroid-like anti-inflammatory activity. Among inflammatory …

Construction and analysis of a ceRNA network and patterns of immune infiltration in chronic rhinosinusitis with nasal polyps: based on data mining and experimental …

J Chen, Q Xing, H Yang, F Yang, Y Luo, W Kong… - Scientific Reports, 2022 - nature.com
Recent studies have revealed the significant role of the competing endogenous RNA
(ceRNA) network in human diseases. However, systematic analysis of the ceRNA …

Osteitis in eosinophilic chronic rhinosinusitis

T Tsuda, K Takeda, R Terada… - Ear, Nose & Throat …, 2024 - journals.sagepub.com
Objectives Eosinophilic chronic rhinosinusitis (ECRS) is an allergic inflammatory disease
characterized by chronic inflammation of the sinus mucosa, and sometimes, osteitis. This …

Eosinophil‐derived interferon‐γ drives transmembrane protein 119–induced new bone formation in chronic rhinosinusitis with nasal polyps

S Jo, BJ Jin, SH Lee, HR Jo, JM Park… - … Forum of Allergy & …, 2023 - Wiley Online Library
Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a chronic inflammatory
sinonasal disease characterized by eosinophilic infiltration and new bone formation. These …