Mutations in the human mitochondrial genome are known to cause an array of diverse
disorders, most of which are maternally inherited, and all of which are associated with …

Mitochondrial dysfunction is central to numerous diseases of oxidative stress. Changes in
mitochondrial DNA (MtDNA) content, often measured as mitochondrial genome to nuclear …

Coffee is a valuable beverage crop due to its characteristic flavor, aroma, and the stimulating
effects of caffeine. We generated a high-quality draft genome of the species Coffea …

Genome sequences reveal that a deluge of DNA from organelles has constantly been
bombarding the nucleus since the origin of organelles. Recent experiments have shown that …

The natural transfer of DNA from mitochondria to the nucleus generates nuclear copies of
mitochondrial DNA (numts) and is an ongoing evolutionary process, as genome sequences …

Mitochondria are organelles with vital functions in almost all eukaryotic cells. Often
described as the cellular 'powerhouses' due to their essential role in aerobic oxidative …

In the past two decades, ancient DNA research has progressed from the retrieval of small
fragments of mitochondrial DNA from a few late Holocene specimens, to large-scale studies …

Mitochondrial gene content is highly variable across extant eukaryotes. The number of
mitochondrial protein genes varies from 3 to 67, while tRNA gene content varies from 0 to …

Mitochondria have been largely considered as 'end-function'organelles, servicing the cell by
producing energy and regulating cell death in response to complex signals. Being cellular …

Despite our tendency to overeat, excessive fat accumulation was prevented in the past, as
any excess weight soon impaired the physical fitness required to gather food, and to either …