Glucagon‐like peptide‐1 receptor agonists and risk of thyroid cancer: a systematic review and meta‐analysis of randomized controlled trials

GA Silverii, M Monami, M Gallo, A Ragni… - Diabetes, Obesity …, 2024 - Wiley Online Library
Aim To conduct a meta‐analysis of randomized clinical trials (RCTs) to investigate whether
there is an association between glucagon‐like peptide‐1 receptor agonist (GLP‐1RA) …

A new era for oral peptides: SNAC and the development of oral semaglutide for the treatment of type 2 diabetes

VR Aroda, L Blonde, RE Pratley - Reviews in Endocrine and Metabolic …, 2022 - Springer
Abstract Glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs) were first
introduced for the treatment of type 2 diabetes (T2D) in 2005. Despite the high efficacy and …

A comprehensive review on weight loss associated with anti-diabetic medications

F Haddad, G Dokmak, M Bader, R Karaman - Life, 2023 - mdpi.com
Obesity is a complex metabolic condition that can have a negative impact on one's health
and even result in mortality. The management of obesity has been addressed in a number of …

Real-world retrospective study into the effects of oral semaglutide (as a switchover or add-on therapy) in type 2 diabetes

R Candido, S Gaiotti, F Giudici, B Toffoli… - Journal of Clinical …, 2023 - mdpi.com
(1) Background: Oral semaglutide represents the first oral GLP-1 RA approved for the
treatment of type 2 diabetes mellitus (T2DM). This real-world retrospective study aimed at …

Comparative efficacy and safety profile of once-weekly Semaglutide versus once-daily Sitagliptin as an add-on to metformin in patients with type 2 diabetes: a …

T Patel, F Nageeta, R Sohail, TS Butt… - Annals of …, 2023 - Taylor & Francis
Background The emergence of genetically-modified human proteins and glucagon-like
peptide-1 (GLP-1) receptor agonists have presented a promising strategy for effectively …

Glycaemic control efficacy of switching from dipeptidyl peptidase‐4 inhibitors to oral semaglutide in subjects with type 2 diabetes: A multicentre, prospective …

S Furusawa, H Nomoto, H Yokoyama… - Diabetes, Obesity …, 2024 - Wiley Online Library
Aim To assess whether oral semaglutide provides better glycaemic control, compared with
dipeptidyl peptidase‐4 inhibitor (DPP‐4i) continuation, in people with type 2 diabetes …

Assessment of Thyroid Carcinogenic Risk and Safety Profile of GLP1-RA Semaglutide (Ozempic) Therapy for Diabetes Mellitus and Obesity: A Systematic Literature …

CVI Feier, RC Vonica, AM Faur, DR Streinu… - International Journal of …, 2024 - mdpi.com
The broadening application of glucagon-like peptide (GLP)-1 receptor agonists, specifically
semaglutide (Ozempic) for the management of diabetes and obesity brings a critical need to …

Suitability and usefulness of a flexible dosing timing of oral semaglutide to maximize benefit in clinical practice: an expert panel

R Candido, C Di Loreto, P Desenzani, P Pantanetti… - Diabetes Therapy, 2024 - Springer
From clinical trials and observational data, oral semaglutide has proven to be the most
effective second-line oral therapy for the management of patients with type 2 diabetes. This …

A Peptide in a Pill–Oral Semaglutide in the Management of Type 2 Diabetes

R Selvarajan, R Subramanian - Diabetes, Metabolic Syndrome …, 2023 - Taylor & Francis
T2DM (type 2 diabetes mellitus) is a chronic and progressive illness with high morbidity and
death rates. Oral semaglutide (Rybelsus®) is a combination of semaglutide, a glucagon-like …

[HTML][HTML] Peptidyl and non-peptidyl oral glucagon-like peptide-1 receptor agonists

HJ Choe, YM Cho - Endocrinology and Metabolism, 2021 - synapse.koreamed.org
Abstract Glucagon-like peptide-1 (GLP-1) receptor agonists are efficacious glucose-lowering
medications with salient benefits for body weight and cardiovascular events. This class of …