Glycoconjugates are major constituents of mammalian cells that are formed via covalent
conjugation of carbohydrates to other biomolecules like proteins and lipids and often …

Influenza A viruses (IAVs) occasionally cross the species barrier and adapt to novel host
species. This requires readjustment of the functional balance of the sialic acid receptor …

The world is experiencing one of the most difficult moments in history with the COVID-19
pandemic, a disease caused by SARS-CoV-2, a new type of coronavirus. Virus infectivity is …

Interactions of influenza A virus (IAV) with sialic acid (SIA) receptors determine viral fitness
and host tropism. Binding to mucus decoy receptors and receptors on epithelial host cells is …

Antigenic mimicry is a fundamental tenet of structure-based vaccinology. Vaccine strategies
for the human immunodeficiency virus type 1 (HIV-1) focus on the mimicry of its envelope …

Gangliosides are glycolipids in which an oligosaccharide headgroup containing one or
more sialic acids is connected to a ceramide. Gangliosides reside in the outer leaflet of the …

Rapid and accurate food pathogen detection is an essential step to preventing foodborne
illnesses. Before detection, removal of bacteria from the food matrix and concentration to …

Cellular glycosylation is characterized by chemical complexity and heterogeneity, which is
challenging to reproduce synthetically. Here we show chemoenzymatic synthesis on phage …

Botulinum toxin (BoNT) is a potent neurotoxin that poses a significant threat as a biowarfare
weapon and a potential bioterrorist tool. Currently, there is a lack of effective …

Proteins are frequently modified by complex carbohydrates (glycans) that play central roles
in maintaining the structural and functional integrity of cells and tissues in humans and lower …