Bone stress injuries

T Hoenig, KE Ackerman, BR Beck… - Nature Reviews …, 2022 - nature.com
Bone stress injuries, including stress fractures, are overuse injuries that lead to substantial
morbidity in active individuals. These injuries occur when excessive repetitive loads are …

[HTML][HTML] Mechanical basis of bone strength: influence of bone material, bone structure and muscle action

NH Hart, S Nimphius, T Rantalainen… - … of musculoskeletal & …, 2017 - ncbi.nlm.nih.gov
This review summarises current understanding of how bone is sculpted through adaptive
processes, designed to meet the mechanical challenges it faces in everyday life and athletic …

Muscle‐bone crosstalk and potential therapies for sarco‐osteoporosis

GB Li, L Zhang, DE Wang, L AIQudsy… - Journal of cellular …, 2019 - Wiley Online Library
The nature of muscle‐bone crosstalk has been historically considered to be only
mechanical, where the muscle is the load applier while bone provides the attachment sites …

[HTML][HTML] Long-term human spaceflight and inflammaging: Does it promote aging?

M Capri, M Conte, E Ciurca, C Pirazzini… - Ageing Research …, 2023 - Elsevier
Spaceflight and its associated stressors, such as microgravity, radiation exposure,
confinement, circadian derailment and disruptive workloads represent an unprecedented …

Osteoporosis and sarcopenia-related traits: A bi-directional Mendelian randomization study

C Liu, N Liu, Y Xia, Z Zhao, T Xiao, H Li - Frontiers in endocrinology, 2022 - frontiersin.org
Background With the advancement of world population aging, age-related osteoporosis
(OP) and sarcopenia (SP) impose enormous clinical and economic burden on society …

Muscle-bone interactions: From experimental models to the clinic? A critical update

MR Laurent, V Dubois, F Claessens… - Molecular and cellular …, 2016 - Elsevier
Bone is a biomechanical tissue shaped by forces from muscles and gravitation.
Simultaneous bone and muscle decay and dysfunction (osteosarcopenia or sarco …

[HTML][HTML] South asian working action group on SARCOpenia (SWAG-SARCO)–A consensus document

M Dhar, N Kapoor, K Suastika, ME Khamseh… - Osteoporosis and …, 2022 - Elsevier
Abstract The South Asian population is rapidly ageing and sarcopenia is likely to become a
huge burden in this region if proper action is not taken in time. Several sarcopenia …

Advancing Intelligent Organ‐on‐a‐Chip Systems with Comprehensive In Situ Bioanalysis

X Li, H Zhu, B Gu, C Yao, Y Gu, W Xu… - Advanced …, 2024 - Wiley Online Library
In vitro models are essential to a broad range of biomedical research, such as pathological
studies, drug development, and personalized medicine. As a potentially transformative …

Role of physical activity in bone–muscle crosstalk: Biological aspects and clinical implications

I Cariati, R Bonanni, F Onorato… - Journal of functional …, 2021 - mdpi.com
Bone and muscle tissues influence each other through the integration of mechanical and
biochemical signals, giving rise to bone–muscle crosstalk. They are also known to secrete …

Preventing bone stress injuries in runners with optimal workload

SJ Warden, WB Edwards, RW Willy - Current osteoporosis reports, 2021 - Springer
Bone stress injuries (BSIs) occur at inopportune times to invariably interrupt training. All BSIs
in runners occur due to an “error” in workload wherein the interaction between the number …