For many years, there was little interest in the biochemistry or physiology of adipose tissue. It
is now well recognized that adipocytes play an important dynamic role in metabolic …

Insulin was discovered 60 years ago [1]; since then its structure has been determined by the
pioneer work of Sanger [2] and by Hodgkin, Blundell and colleagues [3]. Moreover the …

Assays for two distinct phosphatidate phosphohydrolase activities were established based
upon a differential inhibition by N-ethylmaleimide (NEM). The activity that is insensitive to …

1. Toluene-permeabilized rat heart mitochondria have been used to study the regulation of
NAD+-linked isocitrate dehydrogenase and 2-oxoglutarate dehydrogenase by Ca2+ …

The present study was designed to investigate the effects of dietary trans–fatty acids (TFA)
present in Indian vanaspati (partially hydrogenated vegetable oils) in comparison with …

The cDNA for the monocarboxylate transporter MCT2 from rat testis has been cloned and
sequenced. The derived protein sequence shows 82% identity with that from hamster. Rat …

Hepsin, a putative membrane-bound serine protease, was originally identified as a human
liver cDNA clone (Leytus, SP, Loeb, KR, Hagen, FS, Kurachi, K., and Davie, EW (1988) …

The influence of dietary (n-3) compared with (n-6) polyunsatured fatty acids (PUFA) on the
lipid composition and metabolism of adipocytes was evaluated in rats over a period of 1 …

Adenosine, via interaction with A1 adenosine receptors, increases insulin sensitivity and
inhibits lipolysis in adipocytes. To investigate regulation of this system, adipocytes were …

Bromopalmitate and 2-bromopalmitoyl-CoA have been shown to inhibit a variety of enzymes
and proteins associated with lipid metabolism. We found that both of the brominated …