Essential tremor pathology: neurodegeneration and reorganization of neuronal connections

ED Louis, PL Faust - Nature Reviews Neurology, 2020 - nature.com
Essential tremor (ET) is the most common tremor disorder globally and is characterized by
kinetic tremor of the upper limbs, although other clinical features can also occur. Postmortem …

Essential tremor: clinical perspectives and pathophysiology

MK Pan, SH Kuo - Journal of the neurological sciences, 2022 - Elsevier
Essential tremor (ET) is one of the most common neurological disorders and can be highly
disabling. In recent years, studies on the clinical perspectives and pathophysiology have …

Essential tremor

ED Louis - Handbook of clinical neurology, 2023 - Elsevier
Essential tremor (ET) is a chronic and progressive neurologic disease. Its central and
defining clinical feature is a 4–12 Hz kinetic tremor, that is, tremor that occurs during …

'Essential tremor'or 'the essential tremors': is this one disease or a family of diseases?

ED Louis - Neuroepidemiology, 2014 - karger.com
There is accumulating evidence that the entity referred to as 'essential tremor'(ET) is not a
single disease. It may be a family of diseases better referred to as 'the ETs'. This review will …

[HTML][HTML] Essential tremor: a neurodegenerative disease?

J Benito-Leon - Tremor and other hyperkinetic movements, 2014 - ncbi.nlm.nih.gov
Background Essential tremor (ET) is one of the most common neurological disorders among
adults, and is the most common of the many tremor disorders. It has classically been viewed …

Neuronal population activity in the olivocerebellum encodes the frequency of essential tremor in mice and patients

YM Wang, CW Liu, SY Chen, LY Lu, WC Liu… - Science Translational …, 2024 - science.org
Essential tremor (ET) is the most prevalent movement disorder, characterized primarily by
action tremor, an involuntary rhythmic movement with a specific frequency. However, the …

Genomic markers for essential tremor

FJ Jiménez-Jiménez, H Alonso-Navarro… - Pharmaceuticals, 2021 - mdpi.com
There are many reports suggesting an important role of genetic factors in the
etiopathogenesis of essential tremor (ET), encouraging continuing the research for possible …

The pathophysiology and treatment of essential tremor: the role of adenosine and dopamine receptors in animal models

B Kosmowska, J Wardas - Biomolecules, 2021 - mdpi.com
Essential tremor (ET) is one of the most common neurological disorders that often affects
people in the prime of their lives, leading to a significant reduction in their quality of life …

N-methyltetrahydropyridines and pyridinium cations as toxins and comparison with naturally-occurring alkaloids

T Herraiz - Food and Chemical Toxicology, 2016 - Elsevier
Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) and 1-methyl-4-phenylpyridinium
cation (MPP+) are selective dopaminergic neurotoxins producing Parkinsonism. MPTP is …

Elevated blood harmane (1-methyl-9H-pyrido [3, 4-b] indole) concentrations in Parkinson's disease

ED Louis, M Michalec, W Jiang, P Factor-Litvak… - Neurotoxicology, 2014 - Elsevier
Background Parkinson's disease (PD) is a late-life neurodegenerative disease. Genetic and
environmental factors play an etiological role. Harmane (1-methyl-9H-pyrido [3, 4-b] indole) …