Ulcerative colitis (UC) specifically affects the colon and rectum through multifactorial
mechanisms associated with genetic alterations, environmental factors, microbiota, and …

Asthma is a chronic inflammatory airway disease associated with type 2 cytokines
interleukin-4 (IL-4), IL-5, and IL-13, which promote airway eosinophilia, mucus …

Lung diseases are the leading cause of mortality worldwide. The currently available
therapies are not sufficient, leading to the urgent need for new therapies with sustained anti …

Asthma is a chronic inflammatory disorder of the airways. While the local infiltration of
eosinophils and mast cells, and their role in the disease have long been recognized …

Asthma is a common disease that affects 300 million people worldwide. Given the large
number of eosinophils in the airways of people with mild asthma, and verified by data from …

Background Interleukin-23 has been implicated in airway inflammation that is mediated by
type 2 and type 17 cytokines. Whether targeting interleukin-23 in the treatment of asthma …

Obesity is associated with the development of asthma, which is often difficult to control. To
understand the immunological pathways that lead to obesity-associated asthma, we fed …

Asthma has been considered a T helper 2 (TH2) cell-associated inflammatory disease, and
TH2-type cytokines, such as interleukin-4 (IL-4), IL-5 and IL-13, are thought to drive the …

BACKGROUND: Chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) and without
nasal polyps (CRSsNP) is reported to be different in inflammatory patterns of the sinonasal …

Infection with influenza A virus represents a major public health threat worldwide,
particularly in patients with asthma. However, immunity induced by influenza A virus may …