Acute graft-versus-host disease of the gut: considerations for the gastroenterologist

S Naymagon, L Naymagon, SY Wong, HM Ko… - Nature Reviews …, 2017 - nature.com
Haematopoietic stem cell transplantation (HSCT) is central to the management of many
haematological disorders. A frequent complication of HSCT is acute graft-versus-host …

Consequences of Clostridium difficile infection: understanding the healthcare burden

E Bouza - Clinical microbiology and infection, 2012 - Wiley Online Library
C lostridium difficile is the leading cause of infectious nosocomial diarrhoea in developed
countries, with a measured incidence of approximately five episodes per 10 000 days of …

[HTML][HTML] Fecal microbiota transplantation for the treatment of recurrent and severe Clostridium difficile infection in solid organ transplant recipients: a multicenter …

YW Cheng, E Phelps, V Ganapini, N Khan… - American Journal of …, 2019 - Elsevier
Fecal microbiota transplant (FMT) is recommended for Clostridium difficile infection (CDI)
treatment; however, use in solid organ transplantation (SOT) patients has theoretical safety …

Fecal microbiota transplantation for diseases: Therapeutic potential, methodology, risk management in clinical practice

Z Qu, P Tian, B Yang, J Zhao, G Wang, W Chen - Life Sciences, 2022 - Elsevier
Background More than 95% of human diseases may be related to the disturbance of gut
microbes. As a treatment method that extensively regulates the gut microbes, fecal …

[HTML][HTML] Clostridium difficile infection: guideline-based diagnosis and treatment

C Lübbert, E John, L von Müller - Deutsches Ärzteblatt International, 2014 - ncbi.nlm.nih.gov
Background Clostridium difficile (C. difficile) is the pathogen that most commonly causes
nosocomial and antibiotic-associated diarrheal disease. Optimized algorithms for diagnosis …

[HTML][HTML] Fecal microbiota transplantation for refractory Clostridium difficile colitis in solid organ transplant recipients

RJ Friedman-Moraco, AK Mehta, GM Lyon… - American Journal of …, 2014 - Elsevier
Fecal microbiota transplantation (FMT) has been shown to be safe and efficacious in
individuals with refractory Clostridium difficile. It has not been widely studied in individuals …

Recurrent Clostridium difficile infection: from colonization to cure

K Shields, RV Araujo-Castillo, TG Theethira… - Anaerobe, 2015 - Elsevier
Clostridium difficile infection (CDI) is increasingly prevalent, dangerous and challenging to
prevent and manage. Despite intense national and international attention the incidence of …

Fecal microbiota transplantation (FMT) for Clostridium difficile infection: focus on immunocompromised patients

S Di Bella, T Gouliouris, N Petrosillo - Journal of Infection and …, 2015 - Elsevier
Clostridium difficile infection (CDI) is an emerging problem worldwide associated with
significant morbidity, mortality, recurrence rates and healthcare costs. Immunosuppressed …

Challenges for clinical development of vaccines for prevention of hospital-acquired bacterial infections

I Bekeredjian-Ding - Frontiers in immunology, 2020 - frontiersin.org
Increasing antibiotic resistance in bacteria causing endogenous infections has entailed a
need for innovative approaches to therapy and prophylaxis of these infections and raised a …

Detection, treatment, and prevention of Clostridium difficile infection

DL McCollum, JM Rodriguez - Clinical gastroenterology and hepatology, 2012 - Elsevier
Clostridium difficile is a gram-positive anaerobic bacillus responsible for approximately 1 of
5 cases of antibiotic-associated diarrhea. C difficile infection (CDI) is defined by at least 3 …