Survivin, a member of the inhibitor of apoptosis (IAP) protein family that inhibits caspases
and blocks cell death, is highly expressed in most cancers and is associated with a poor …

Betel nut (BN), betel quid (BQ) and products derived from them are widely used as a socially
endorsed masticatory product. The addictive nature of BN/BQ has resulted in its widespread …

Head-and-neck squamous cell carcinoma (HNSCC) is the sixth most common cancer
worldwide, and its incidence is growing. Although environmental carcinogens and …

Survivin is a member of the family of apoptosis inhibitory proteins with increased expression
level in most cancerous tissues. Evidence shows that survivin plays regulatory roles in …

Oral squamous cell carcinoma (OSCC) and oropharyngeal squamous cell carcinoma
(OPSCC) are the most common types of cancers in the head and neck region (HNSCC) …

The overexpression of histone deacetylases (HDACs) has been observed in many cancers
and inhibition of specific HDAC has emerged as a new target for cancer therapy. The …

Background MicroRNAs (miRNAs) have been regarded as a critical factor in targeting
oncogenes or tumor suppressor genes in tumorigenesis. The genetic predisposition of …

Background The past 2 decades have seen an increased incidence of head and neck
squamous cell carcinoma (HNSCC) in a nontraditional, low‐risk patient population (ie,≤ 45 …

Survivin holds significant importance as a member of the inhibitor of apoptosis protein (IAP)
family due to its predominant expression in tumours rather than normal terminally …

Background The survivin polymorphisms have been shown to confer genetic susceptibility to
various tumors, but the results are inconsistent. In order to accomplish a more precise …