Covering: up to September 2015 Meroterpenoids are hybrid natural products that partially
originate from the terpenoid pathway. The meroterpenoids derived from fungi display quite …

Covering: 2013 to 2022 In this review, we provide an overview elucidating the biosynthetic
pathway and heterologous production of fungal indole diterpenes (IDTs). Based on the …

Ascofuranone (AF) and ascochlorin (AC) are meroterpenoids produced by various
filamentous fungi, including Acremonium egyptiacum (synonym: Acremonium …

As with many microbes, entomopathogenic fungi from the genus Metarhizium produce a
plethora of small molecule metabolites, often referred to as secondary metabolites. Although …

Fungal specialized metabolites play an important role in the environment and have
impacted human health and survival significantly. These specialized metabolites are often …

The significant structural diversity and potent bioactivity of the fungal indole diterpenes
(IDTs) has attracted considerable interest in their biosynthesis. Although substantial skeletal …

A modular and hierarchical DNA assembly platform for synthetic biology based on Golden
Gate (Type IIS restriction enzyme) cloning is described. This enabling technology, termed …

Nodulisporic acids comprise a group of valuable indole diterpenes that exhibit potent
insecticidal activities. We report the identification of a gene cluster in the genome of the …

The late-stage biosynthetic pathway of the indole diterpene shearinine involving four
enzymatic reactions (JanQDOJ) was elucidated by an efficient heterologous expression …

Indole-diterpenes (IDTs) such as the aflatrems, janthitrems, lolitrems, paspalitrems,
penitrems, shearinines, sulpinines, and terpendoles are biogenetically related but …