Lysine acetylation is a conserved, reversible, post-translational protein modification
regulated by lysine acetyltransferases (KATs) and lysine deacetylases (KDACs; also known …

Polypyrimidine tract‐binding protein (PTB), as a member of the heterogeneous nuclear
ribonucleoprotein family, functions by rapidly shuttling between the nucleus and the …

Polypyrimidine Tract Binding Protein (PTB) is an intensely studied RNA binding protein
involved in several post-transcriptional regulatory events of gene expression. Initially …

Cardiovascular disease (CVD) remains a leading cause of mortality worldwide despite
advances in its prevention and management. A comprehensive understanding of factors …

Glioblastoma multiforme is resistant to conventional anti-tumoral treatments due to its
infiltrative nature and capability of relapse; therefore, research efforts focus on characterizing …

Polypyrimidine tract-binding protein 1 (PTBP1) is a member of the heterogeneous nuclear
ribonucleoprotein (hnRNP) family, which plays a key role in alternative splicing of precursor …

The central dogma of molecular biology illustrates the importance of mRNAs as critical
mediators between genetic information encoded at the DNA level and proteomes …

Alternative splicing is a regulatory mechanism essential for cell differentiation and tissue
organization. More than 90% of human genes are regulated by alternative splicing events …

Throughout life, animals face a variety of challenges such as developmental growth, the
presence of toxins, or changes in temperature. Neuronal circuits and synapses respond to …

In recent years, eukaryotic long non-coding RNAs (lncRNAs) have been identified as
important factors involved in a wide variety of biological processes, including histone …