A review of colorectal cancer in terms of epidemiology, risk factors, development, symptoms and diagnosis
T Sawicki, M Ruszkowska, A Danielewicz… - Cancers, 2021 - mdpi.com
Simple Summary According to the available data, colorectal cancer (CRC) is one of the most
common malignant neoplasms. Depending on the location, type of cancer or gender, it is …
common malignant neoplasms. Depending on the location, type of cancer or gender, it is …
Genetic and biological hallmarks of colorectal cancer
Colorectal cancer has served as a genetic and biological paradigm for the evolution of solid
tumors, and these insights have illuminated early detection, risk stratification, prevention …
tumors, and these insights have illuminated early detection, risk stratification, prevention …
Epigenetic alterations in colorectal cancer: emerging biomarkers
Colorectal cancer (CRC) is a leading cause of cancer deaths worldwide. One of the
fundamental processes driving the initiation and progression of CRC is the accumulation of …
fundamental processes driving the initiation and progression of CRC is the accumulation of …
[HTML][HTML] Colorectal cancer carcinogenesis: a review of mechanisms
Colorectal cancer (CRC) is the second most common cancer in women and the third most
common in men globally. CRC arises from one or a combination of chromosomal instability …
common in men globally. CRC arises from one or a combination of chromosomal instability …
Molecular pathogenesis of sporadic colorectal cancers
H Yamagishi, H Kuroda, Y Imai, H Hiraishi - Chinese journal of cancer, 2016 - Springer
Colorectal cancer (CRC) results from the progressive accumulation of genetic and
epigenetic alterations that lead to the transformation of normal colonic mucosa to …
epigenetic alterations that lead to the transformation of normal colonic mucosa to …
The long noncoding RNA CCAT2 induces chromosomal instability through BOP1-AURKB signaling
B Chen, MP Dragomir, L Fabris, R Bayraktar… - Gastroenterology, 2020 - Elsevier
Background & Aims Chromosomal instability (CIN) is a carcinogenesis event that promotes
metastasis and resistance to therapy by unclear mechanisms. Expression of the colon …
metastasis and resistance to therapy by unclear mechanisms. Expression of the colon …
Quercetin: a functional dietary flavonoid with potential chemo‐preventive properties in colorectal cancer
Recently, an intense attention has been paid to the application of natural compounds as a
novel therapeutic strategy for cancer treatment. Quercetin, a natural flavonol present in many …
novel therapeutic strategy for cancer treatment. Quercetin, a natural flavonol present in many …
The forkhead-box family of transcription factors: key molecular players in colorectal cancer pathogenesis
P Laissue - Molecular cancer, 2019 - Springer
Colorectal cancer (CRC) is the third most commonly occurring cancer worldwide and the
fourth most frequent cause of death having an oncological origin. It has been found that …
fourth most frequent cause of death having an oncological origin. It has been found that …
Clinical relevance of colorectal cancer molecular subtypes
N Rodriguez-Salas, G Dominguez, R Barderas… - Critical reviews in …, 2017 - Elsevier
Colorectal cancer (CRC) is characterized by alteration of critical pathways such TP53
inactivation, BRAF, PI3CA mutations, APC inactivation, KRAS, TGF-β, CTNNB mutations …
inactivation, BRAF, PI3CA mutations, APC inactivation, KRAS, TGF-β, CTNNB mutations …
The role of mSEPT9 in screening, diagnosis, and recurrence monitoring of colorectal cancer
J Sun, F Fei, M Zhang, Y Li, X Zhang, S Zhu, S Zhang - BMC cancer, 2019 - Springer
Background The application of circulating, cell-free, methylated Septin9 (m SEPT9) DNA in
screening and recurrence monitoring is highly promising. CpG island methylator phenotype …
screening and recurrence monitoring is highly promising. CpG island methylator phenotype …