The role of short-chain fatty acids in the interplay between gut microbiota and diet in cardio-metabolic health

A Nogal, AM Valdes, C Menni - Gut microbes, 2021 - Taylor & Francis
The gut microbiota plays an important role in cardio-metabolic diseases with diet being
among the strongest modulators of gut microbiota composition and function. Resistant …

The gut microbiota in obesity and weight management: microbes as friends or foe?

M Van Hul, PD Cani - Nature Reviews Endocrinology, 2023 - nature.com
Obesity is caused by a long-term difference between energy intake and expenditure—an
imbalance that is seemingly easily restored by increasing exercise and reducing caloric …

Acarbose treatment affects the serum levels of inflammatory cytokines and the gut content of bifidobacteria in C hinese patients with type 2 diabetes mellitus: 阿卡波糖 …

B Su, H Liu, J Li, Y Sunli, B Liu, D Liu… - Journal of …, 2015 - Wiley Online Library
摘要背景: 研究对中国2 型糖尿病患者在常规治疗的基础上加用阿卡波糖后对患者粪便肠道菌群
及血清炎症因子的影响. 方法: 95 名2 型糖尿病患者在常规治疗的基础上随机分为两组, A 组59 …

High-fat, western-style diet, systemic inflammation, and gut microbiota: a narrative review

IJ Malesza, M Malesza, J Walkowiak, N Mussin… - Cells, 2021 - mdpi.com
The gut microbiota is responsible for recovering energy from food, providing hosts with
vitamins, and providing a barrier function against exogenous pathogens. In addition, it is …

Role of the gut–brain axis in energy and glucose metabolism

HR Wachsmuth, SN Weninger, FA Duca - Experimental & molecular …, 2022 - nature.com
The gastrointestinal tract plays a role in the development and treatment of metabolic
diseases. During a meal, the gut provides crucial information to the brain regarding …

The intestinal microbiota fuelling metabolic inflammation

H Tilg, N Zmora, TE Adolph, E Elinav - Nature Reviews Immunology, 2020 - nature.com
Low-grade inflammation is the hallmark of metabolic disorders such as obesity, type 2
diabetes and nonalcoholic fatty liver disease. Emerging evidence indicates that these …

[HTML][HTML] Free fatty acid receptors in health and disease

I Kimura, A Ichimura, R Ohue-Kitano… - Physiological …, 2019 - journals.physiology.org
Fatty acids are metabolized and synthesized as energy substrates during biological
responses. Long-and medium-chain fatty acids derived mainly from dietary triglycerides, and …

Regulation of the intestinal barrier by nutrients: The role of tight junctions

T Suzuki - Animal Science Journal, 2020 - Wiley Online Library
Tight junctions (TJs) play an important role in intestinal barrier function. TJs in intestinal
epithelial cells are composed of different junctional molecules, such as claudin and …

[HTML][HTML] Negative effects of a high-fat diet on intestinal permeability: a review

MW Rohr, CA Narasimhulu, TA Rudeski-Rohr… - Advances in …, 2020 - Elsevier
The intestinal tract is the largest barrier between a person and the environment. In this role,
the intestinal tract is responsible not only for absorbing essential dietary nutrients, but also …

You are what you eat: diet, health and the gut microbiota

N Zmora, J Suez, E Elinav - Nature reviews Gastroenterology & …, 2019 - nature.com
Since the renaissance of microbiome research in the past decade, much insight has
accumulated in comprehending forces shaping the architecture and functionality of resident …