Conspectus The expression of genes in a cell in response to external signals or internal
programs occurs within an environment that is compartmentalized and dense …

Among the many important biopolymers, DNA has been a key component in material
sciences and nanotechnology. We have focused on the fabrication of metal …

Cell-free gene expression in localized DNA brushes on a biochip has been shown to
depend on gene density and orientation, suggesting that brushes form compartments with …

The development of a strategy for the assembly of nanoscale building blocks, in particular,
anisotropic nanoparticles, into desired structures is important for the construction of …

We investigated the collective conformational response of DNA polymer brushes to
condensation induced by the trivalent cation spermidine. DNA brushes, a few kilobase-pairs …

Large macromolecular assemblies are widespread in all cell types with diverse structural
and functional roles. Whether localized to membranes, nuclei, or cytoplasm, multimeric …

Metallic films with a controlled gradient can be fabricated on substrates via electrochemically
induced metallic ion deposition. This method uses a syringe pump to uniformly move down …

Biomarkers are biological measures used for clinical assessment, whether an individual has
a particular medical condition or to monitor and predict health states in individuals. Sensitive …

Biomarkers are biological measures used for clinical assessment, whether an individual has
a particular medical condition or to monitor and predict health states in individuals. Sensitive …

DNA-transactions in a living cell take place in an intracellular compartment of highly dense
DNA. At close proximity between overlapping DNA segments within this segregated …