Andrographolide, a diterpene lactone from Andrographis paniculata and its therapeutic promises in cancer

MT Islam, ES Ali, SJ Uddin, MA Islam, S Shaw, IN Khan… - Cancer letters, 2018 - Elsevier
The diterpene lactone andrographolide, isolated from Andrographis paniculata, has been
proven to possess several important protective biological activities, including antioxidant …

Multi-targeting andrographolide and its natural analogs as potential therapeutic agents

V Kishore, N Sastry Yarla, A Bishayee… - Current topics in …, 2017 - ingentaconnect.com
Andrographis paniculata (A. paniculata) is a medicinal plant used in the Indian and Chinese
traditional medicinal systems for its various beneficial properties of therapeutics. This is due …

Prevention and treatment of cancer targeting chronic inflammation: research progress, potential agents, clinical studies and mechanisms

Y Zhang, W Kong, J Jiang - Science China Life Sciences, 2017 - Springer
Numerous experimental and clinical studies indicate that chronic inflammation is closely
related to the initiation, progression, and spread of cancer, in which proinflammatory …

Andrographolide‐loaded solid lipid nanoparticles enhance anti‐cancer activity against head and neck cancer and precancerous cells

H Li, X Qu, W Qian, Y Song, C Wang, W Liu - Oral Diseases, 2022 - Wiley Online Library
Background Increasing evidence indicates that andrographolide (ADG) exhibits anti‐cancer
activity against various cancer cell lines. However, its high hydrophobicity and poor …

Inhalable Andrographolide-β-cyclodextrin Inclusion Complexes for Treatment of Staphylococcus aureus Pneumonia by Regulating Immune Responses

T Zhang, L Zhu, M Li, Y Hu, E Zhang… - Molecular …, 2017 - ACS Publications
Bacterial pneumonia is a serious disease with high mortality if no appropriate and
immediate therapy is available. Andrographolide (AG) is an anti-inflammatory agent …

Anticancer potential of labdane diterpenoid lactone “andrographolide” and its derivatives: a semi-synthetic approach

V Sharma, T Sharma, S Kaul, KK Kapoor… - Phytochemistry …, 2017 - Springer
Natural products have been a great source of pharmaceuticals since ages. Vast screening of
natural products from different sources has led to the discovery of plethora of …

Dose responsive efficacy of umbelliferone on lipid peroxidation, anti-oxidant, and xenobiotic metabolism in DMBA-induced oral carcinogenesis

A Vijayalakshmi, G Sindhu - Biomedicine & Pharmacotherapy, 2017 - Elsevier
This study evaluated the chemopreventive potential of umbelliferone (UMB) on 7, 12-
dimethylbenz [a] anthracene (DMBA) induced hamster buccal pouch carcinogenesis. The …

[PDF][PDF] Saffron reduction of 7, 12-dimethylbenz [a] anthracene-induced hamster buccal pouch carcinogenesis

S Manoharan, SA Wani… - … Pacific Journal of …, 2013 - pdfs.semanticscholar.org
Our aim was to investigate the chemopreventive potential of saffron in DMBA-induced
hamster buccal pouch carcinogenesis. Assessment was by monitoring the percentage of …

Chemopreventive potential of esculetin in 7, 12-dimethylbenz (a) anthracene-induced hamster buccal pouch carcinogenesis

R Selvasundaram, S Manoharan, R Buddhan… - Molecular and cellular …, 2018 - Springer
Dimethylbenz (a) anthracene (DMBA)-induced hamster buccal pouch carcinogenesis is
widely preferred to assess the tumor-inhibiting efficacy of the medicinal plants or their …

Protective effects of Scutellaria barbata against rat liver tumorigenesis

ZJ Dai, WY Wu, HF Kang, XB Ma… - Asian Pacific Journal …, 2013 - journal.waocp.org
Scutellaria barbata D. Don (S. barbata), a traditional Chinese medicine, is used to treat
cancers, inflammation, and urinary diseases. This study aimed to determine any protective …