Hepatocytes and the art of killing Plasmodium softly
C Marques-da-Silva, C Schmidt-Silva, SP Kurup - Trends in Parasitology, 2024 - cell.com
The Plasmodium parasites that cause malaria undergo asymptomatic development in the
parenchymal cells of the liver, the hepatocytes, prior to infecting erythrocytes and causing …
parenchymal cells of the liver, the hepatocytes, prior to infecting erythrocytes and causing …
Inherently Reduced Expression of ASC Restricts Caspase-1 Processing in Hepatocytes and Promotes Plasmodium Infection
C Marques-da-Silva, C Schmidt-Silva… - The Journal of …, 2024 - journals.aai.org
Inflammasome-mediated caspase-1 activation facilitates innate immune control of
Plasmodium in the liver, thereby limiting the incidence and severity of clinical malaria …
Plasmodium in the liver, thereby limiting the incidence and severity of clinical malaria …
[HTML][HTML] Pyroptosis: Induction and inhibition strategies for immunotherapy of diseases
J Wu, H Wang, P Gao, S Ouyang - Acta Pharmaceutica Sinica B, 2024 - Elsevier
Cell death is a central process for organismal health. Pyroptosis, namely pyroptotic cell
death, is recognized as a critical type that disrupts membrane and triggers pro-inflammatory …
death, is recognized as a critical type that disrupts membrane and triggers pro-inflammatory …
LC3B labeling of the parasitophorous vacuole membrane of Plasmodium berghei liver stage parasites depends on the V‐ATPase and ATG16L1
A Bindschedler, J Schmuckli‐Maurer… - Molecular …, 2024 - Wiley Online Library
The protozoan parasite Plasmodium, the causative agent of malaria, undergoes an
obligatory stage of intra‐hepatic development before initiating a blood‐stage infection …
obligatory stage of intra‐hepatic development before initiating a blood‐stage infection …
AIM2 enhances Candida albicans infection through promoting macrophage apoptosis via AKT signaling
Q Jiang, Y Chen, S Zheng, L Sui, D Yu, F Qing… - Cellular and Molecular …, 2024 - Springer
Candida albicans is among the most prevalent invasive fungal pathogens for
immunocompromised individuals and novel therapeutic approaches that involve immune …
immunocompromised individuals and novel therapeutic approaches that involve immune …
[HTML][HTML] Unraveling the intricacies of host-pathogen interaction through single-cell genomics
E Gioacchino, K Vandelannoote, AA Ruberto… - Microbes and …, 2024 - Elsevier
Single-cell genomics provide researchers with tools to assess host-pathogen interactions at
a resolution previously inaccessible. Transcriptome analysis, epigenome analysis, and …
a resolution previously inaccessible. Transcriptome analysis, epigenome analysis, and …
[HTML][HTML] NLRP3 and AIM2 inflammasomes exacerbate the pathogenic Th17 cell response to eggs of the helminth Schistosoma mansoni
MSKM Kumari, P Liu, K Jump, Y Morales, EA Miller… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Infection with the helminth Schistosoma mansoni can cause exacerbated morbidity and
mortality via a pathogenic host CD4 T cell-mediated immune response directed against …
mortality via a pathogenic host CD4 T cell-mediated immune response directed against …
NLRP3 and AIM2 inflammasomes exacerbate the pathogenic Th17 cell response to eggs of the helminth Schistosoma mansoni
M Suresh Kumar Meena Kumari, P Liu, K Jump… - bioRxiv, 2024 - biorxiv.org
Infection with the helminth Schistosoma mansoni can cause exacerbated morbidity and
mortality via a pathogenic host CD4 T cell-mediated immune response directed against …
mortality via a pathogenic host CD4 T cell-mediated immune response directed against …
Characterization of field-derived Plasmodium falciparum liver-stage infection with in vitro primary human hepatocytes.
Recent advances in establishing Plasmodium falciparum liver stages with human
hepatocytes have provided new insights into human hepatocyte hostparasite interactions …
hepatocytes have provided new insights into human hepatocyte hostparasite interactions …