Lipids are essential metabolites, which function as energy sources, structural components
and signalling mediators. Most cells are able to convert carbohydrates into fatty acids, which …

Peroxisomes are subcellular organelles that play a central role in human physiology by
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …

Dietary mono-unsaturated fatty acids (MUFAs) are linked to longevity in several species. But
the mechanisms by which MUFAs extend lifespan remain unclear. Here we show that an …

In mammals, white adipose tissues are largely divided into visceral epididymal adipose
tissue (EAT) and subcutaneous inguinal adipose tissue (IAT) with distinct metabolic …

Eukaryotic cells contain several membrane-separated organelles to compartmentalize
distinct metabolic reactions. However, it has remained unclear how these organelle systems …

Cells prepare for fluctuations in nutrient availability by storing energy in the form of neutral
lipids in organelles called Lipid Droplets (LDs). Upon starvation, fatty acids (FAs) released …

Peroxisomes are involved in multiple metabolic processes, including fatty acid oxidation,
ether lipid synthesis, and reactive oxygen species (ROS) metabolism. Recent studies …

Peroxisomes are essential metabolic organelles, well known for their roles in the
metabolism of complex lipids and reactive ionic species. In the past 10 years, peroxisomes …

Background Peroxisomes are single membrane-bound organelles named for their role in
hydrogen peroxide production and catabolism. However, their cellular functions extend well …

Lipid droplets (LDs) are cellular organelles rich in neutral lipids such as triglycerides and
cholesterol esters that are coated by a phospholipid monolayer and associated proteins …