The emergence of phase separation as an organizing principle in bacteria

CA Azaldegui, AG Vecchiarelli, JS Biteen - Biophysical journal, 2021 - cell.com
Recent investigations in bacteria suggest that membraneless organelles play a crucial role
in the subcellular organization of bacterial cells. However, the biochemical functions and …

Cold shock response in bacteria

Y Zhang, CA Gross - Annual Review of Genetics, 2021 - annualreviews.org
Bacteria often encounter temperature fluctuations in their natural habitats and must adapt to
survive. The molecular response of bacteria to sudden temperature upshift or downshift is …

α-Proteobacterial RNA degradosomes assemble liquid-liquid phase-separated RNP bodies

N Al-Husini, DT Tomares, O Bitar, WS Childers… - Molecular cell, 2018 - cell.com
Ribonucleoprotein (RNP) granules play an important role in organizing eukaryotic mRNA
metabolism via liquid-liquid phase separation (LLPS) of mRNA decay factors into membrane …

BR-bodies provide selectively permeable condensates that stimulate mRNA decay and prevent release of decay intermediates

N Al-Husini, DT Tomares, ZJ Pfaffenberger… - Molecular cell, 2020 - cell.com
Biomolecular condensates play a key role in organizing RNAs and proteins into
membraneless organelles. Bacterial RNP-bodies (BR-bodies) are a biomolecular …

Bacterial RNA degradosomes: molecular machines under tight control

A Tejada-Arranz, V de Crecy-Lagard… - Trends in biochemical …, 2020 - cell.com
Bacterial RNA degradosomes are multienzyme molecular machines that act as hubs for post-
transcriptional regulation of gene expression. The ribonuclease activities of these …

RNase E and the high-fidelity orchestration of RNA metabolism

KJ Bandyra, BF Luisi - Microbiology spectrum, 2018 - Am Soc Microbiol
The bacterial endoribonuclease RNase E occupies a pivotal position in the control of gene
expression, as its actions either commit transcripts to an irreversible fate of rapid destruction …

Chloroplast ribosome biogenesis factors

LM Schmid, N Manavski, W Chi… - Plant and Cell …, 2024 - academic.oup.com
The formation of chloroplasts can be traced back to an ancient event in which a eukaryotic
host cell containing mitochondria ingested a cyanobacterium. Since then, chloroplasts have …

Getting closer to decrypting the phase transitions of bacterial biomolecules

K Sołtys, A Tarczewska, D Bystranowska, N Sozańska - Biomolecules, 2022 - mdpi.com
Liquid–liquid phase separation (LLPS) of biomolecules has emerged as a new paradigm in
cell biology, and the process is one proposed mechanism for the formation of membraneless …

Phase‐separated bacterial ribonucleoprotein bodies organize mRNA decay

NS Muthunayake, DT Tomares… - Wiley …, 2020 - Wiley Online Library
In bacteria, mRNA decay is controlled by megadalton scale macromolecular assemblies
called,“RNA degradosomes,” composed of nucleases and other RNA decay associated …

Regulation of mRNA decay in E. coli

BK Mohanty, SR Kushner - Critical reviews in biochemistry and …, 2022 - Taylor & Francis
Detailed studies of the Gram-negative model bacterium, Escherichia coli, have
demonstrated that post-transcriptional events exert important and possibly greater control …