Recent pre-clinical and clinical studies have shown that stem cell-based therapies hold
tremendous promise for the treatment of human disease. Mesenchymal stem cells (MSC) …

Imaging has become an indispensable tool in the study of cancer biology and in clinical
prognosis and treatment. The rapid advances in high resolution fluorescent imaging at …

The administration of inactivated tumor cells is known to induce a potent antitumor immune
response; however, the efficacy of such an approach is limited by its inability to kill tumor …

Cell-based drug delivery systems have shown promising capability for tumor-targeted
therapy owing to the intrinsic tumor-homing and drug-carrying property of some living cells …

The poor prognosis of patients with aggressive and invasive cancers combined with toxic
effects and short half-life of currently available treatments necessitate development of more …

Therapeutically engineered stem cells have shown promise for glioblastoma multiforme
(GBM) therapy; however, key preclinical studies are urgently needed for their clinical …

The recent Food and Drug Administration approval of immunogenic oncolytic virus (OV) has
opened a new era in the treatment of advanced melanoma; however, approximately 50% of …

Lentiviruses have been extensively used as gene delivery vectors since the mid-1990s.
Usually derived from the human immunodeficiency virus genome, they mediate efficient …

Background The current treatment regimen for malignant glioblastoma multiforme (GBM) is
tumor resection followed by chemotherapy and radiation therapy. Despite the proven safety …

As our understanding of stem-cell behaviour rapidly increases, more and more reports
suggest that use of stem-cell therapy will extend well beyond regenerative medicine in the …