A renewed concept on the MAPK signaling pathway in cancers: Polyphenols as a choice of therapeutics

J Anjum, S Mitra, R Das, R Alam, A Mojumder… - Pharmacological …, 2022 - Elsevier
Abnormalities in the mitogen-activated protein kinase (MAPK) signaling pathway are a key
contributor to the carcinogenesis process and have therefore been implicated in several …

Advances on natural polyphenols as anticancer agents for skin cancer

S Sajadimajd, R Bahramsoltani, A Iranpanah… - Pharmacological …, 2020 - Elsevier
Polyphenols are one of most important phytochemicals distributing in herb plants,
vegetables and fruits, which known as important anticancer agents. Given the high …

[HTML][HTML] Anticancer and apoptosis‑inducing effects of quercetin in vitro and in vivo

M Hashemzaei, A Delarami Far… - Oncology …, 2017 - … .spandidos-publications.com
The present study focused on the elucidation of the putative anticancer potential of
quercetin. The anticancer activity of quercetin at 10, 20, 40, 80 and 120 µM was assessed in …

Fisetin and quercetin: promising flavonoids with chemopreventive potential

D Kashyap, VK Garg, HS Tuli, MB Yerer, K Sak… - Biomolecules, 2019 - mdpi.com
Despite advancements in healthcare facilities for diagnosis and treatment, cancer remains
the leading cause of death worldwide. As prevention is always better than cure, efficient …

Flavonoids in cancer metastasis

A Liskova, L Koklesova, M Samec, K Smejkal… - Cancers, 2020 - mdpi.com
Metastasis represents a serious complication in the treatment of cancer. Flavonoids are
plant secondary metabolites exerting various health beneficiary effects. The effects of …

Molecular and cellular mechanisms of propolis and its polyphenolic compounds against cancer

N Oršolić, M Jazvinšćak Jembrek - International journal of molecular …, 2022 - mdpi.com
In recent years, interest in natural products such as alternative sources of pharmaceuticals
for numerous chronic diseases, including tumors, has been renewed. Propolis, a natural …

Review of natural compounds for potential skin cancer treatment

TN Chinembiri, LH Du Plessis, M Gerber, JH Hamman… - Molecules, 2014 - mdpi.com
Most anti-cancer drugs are derived from natural resources such as marine, microbial and
botanical sources. Cutaneous malignant melanoma is the most aggressive form of skin …

Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways

M Granato, C Rizzello, MSG Montani, L Cuomo… - The Journal of nutritional …, 2017 - Elsevier
Quercetin, a bioflavonoid contained in several vegetables daily consumed, has been
studied for long time for its antiinflammatory and anticancer properties. Quercetin interacts …

Quercetin-ferrum nanoparticles enhance photothermal therapy by modulating the tumor immunosuppressive microenvironment

L Li, M Zhang, T Liu, J Li, S Sun, J Chen, Z Liu… - Acta Biomaterialia, 2022 - Elsevier
Photothermal therapy (PTT) was reported to induce synergistic immunogenic cell death
(ICD) which may convert tumor cells into “therapeutic vaccines”. However, this is often …

[HTML][HTML] New insights into quercetin nanoformulations for topical delivery

K Wadhwa, V Kadian, V Puri, BY Bhardwaj, A Sharma… - Phytomedicine Plus, 2022 - Elsevier
Background Quercetin is one of the most critical endogenous anti-oxidants used widely in
cosmetics, nutraceuticals, and pharmaceuticals products for skincare and therapeutics due …