The nervous and immune systems are the primary sensory interfaces of the body, allowing it
to recognize, process, and respond to various stimuli from both the external and internal …

Neural circuits are characterized as interconnecting neuron networks connected by
synapses. Some kinds of gene expression and/or functional changes of neurons and …

Originally identified in fibroblasts, Protease Inhibitor (PI) 16 was recently shown to be crucial
for the development of neuropathic pain via effects on blood-nerve barrier permeability and …

As chemotherapy is still a cornerstone of colorectal cancer (CRC) treatment, chemotherapy-
induced peripheral neuropathy (CIPN) presents significant clinical challenges, affecting …

The nervous system is the dominant regulatory system in the human body. The traditional
theory is that tumors lack innervation. However, an increasing number of studies have …

Soft tissue injuries often involve muscle and peripheral nerves and are qualitatively distinct
from single-tissue injuries. Prior research suggests that damaged innervation compromises …

Bupi Yichang formula (BPYCF) has shown the anti-cancer potential; however, its effects on
colon cancer and the mechanisms remain unknown. This study intended to explore the …

Background To investigate the expression levels and diagnostic value of glial cell line-
derived neurotrophic factor (GDNF), carcinoembryonic antigen (CEA) and carbohydrate …

Colorectal cancer survivors are at increased risk of developing neurological issues,
particularly peripheral neuropathy and chronic pain. Although pre-existing neuropathy is a …

Chronic pain represents a significant unmet therapeutic need, particularly for those chronic
pain states with a neuropathic component (ie, a lesion or disease of the somatosensory …