Group B streptococcus (GBS) is a gram-positive bacteria that asymptomatically colonizes the
vaginal tract. However, during pregnancy maternal GBS colonization greatly predisposes …

Survivors of preterm birth struggle with multitudes of disabilities due to improper in utero
programming of various tissues and organ systems contributing to adult-onset diseases at a …

Epigenetic regulation of imprinted genes is regarded as a highly plausible explanation for
linking dietary exposures in early life with the onset of diseases during childhood and …

Influenza A virus (IAV) infection during pregnancy causes severe maternal and perinatal
complications, despite a lack of vertical transmission of IAV across the placenta. Here, we …

Streptococcus agalactiae, or group B Streptococcus (GBS), is a common perinatal pathogen.
GBS colonization of the vaginal mucosa during pregnancy is a risk factor for invasive …

Background Pre-term birth (PTB) remains the leading cause of infant mortality and morbidity.
Its etiology is multifactorial, with a strong genetic component. Genetic predisposition for the …

Trophoblast immune cell interactions are central events in the immune microenvironment at
the maternal-fetal interface. Their abnormalities are potential causes of various pregnancy …

The transcription factor nuclear factor kappa B (NF κB) controls the expression of over 400
genes, some of which are associated with reproductive events. During implantation, immune …

Maternal fatty acid and lipid metabolism undergoes changes during pregnancy to facilitate
fetal growth and development. Different types of fatty acids have different roles in …

Invasive bacterial infections during pregnancy are a major risk factor for preterm birth,
stillbirth, and fetal injury. Group B streptococci (GBS) are Gram-positive bacteria that …