This article provides a comprehensive review of biosensing with DNAzymes, providing an
overview of different sensing applications while highlighting major progress and seminal …

Metal ions are essential to many chemical, biological, and environmental processes. In the
past two decades, many DNA-based metal sensors have emerged. While the main …

This review aims at juxtaposing common versus distinct structural and functional strategies
that are applied by aptamers, riboswitches, and ribozymes/DNAzymes. Focusing on recently …

Sensors are devices that respond to physical or chemical stimuli and produce detectable
signals. 1r4 They are a critical extension of human perception of the world in many aspects …

Conspectus DNA-based enzymes, or DNAzymes, are not known to exist in Nature but can
be isolated from random-sequence DNA pools using test tube selection techniques. Since …

Since the initial discovery of ribozymes in the early 1980s, catalytic nucleic acids have been
used in different areas. Compared with protein enzymes, catalytic nucleic acids are …

DNAzymes have several practical advantages when compared to protein enzymes and
ribozymes and thus have been extensively used for developing analytical techniques. 6− 18 …

DNAzymes are catalytically active DNA molecules that are obtained via in vitro selection.
RNA-cleaving DNAzymes have attracted significant attention for both therapeutic and …

In addition to storage of genetic information, DNA can also catalyze various reactions. RNA-
cleaving DNAzymes are the catalytic DNAs discovered the earliest, and they can cleave …

Threose nucleic acid has been considered a potential evolutionary progenitor of RNA
because of its chemical simplicity, base pairing properties and capacity for higher-order …