[PDF][PDF] A hMTR4‐PDIA3P1‐miR‐125/124‐TRAF6 regulatory axis and its function in NF kappa B signaling and chemoresistance

C Xie, LZ Zhang, ZL Chen, WJ Zhong, JH Fang… - …, 2020 - Wiley Online Library
Background and Aims DNA damage‐induced NF‐κB activation is a major obstacle to
effective antitumour chemotherapy. Long noncoding RNAs (lncRNAs) that regulate …

IRF2BP2: A new player in the regulation of cell homeostasis

R Ramalho-Oliveira, B Oliveira-Vieira… - Journal of leukocyte …, 2019 - academic.oup.com
Abstract The IRF2BP2 (IFN regulatory factor 2 binding protein 2) protein was identified as a
nuclear protein that interacts with IFN regulatory factor 2 (IRF-2) and is an IRF-2-dependent …

The transcriptional co-factor IRF2BP2: A new player in tumor development and microenvironment

TP Pastor, BC Peixoto, JPB Viola - Frontiers in Cell and …, 2021 - frontiersin.org
Interferon regulatory factor 2-binding protein 2 (IRF2BP2) encodes a member of the IRF2BP
family of transcriptional regulators, which includes IRF2BP1, IRF2BP2, and IRF2BPL …

SP3-enabled rapid and high coverage chemoproteomic identification of cell-state–dependent redox-sensitive cysteines

HS Desai, T Yan, F Yu, AW Sun, M Villanueva… - Molecular & Cellular …, 2022 - ASBMB
Proteinaceous cysteine residues act as privileged sensors of oxidative stress. As reactive
oxygen and nitrogen species have been implicated in numerous pathophysiological …

Transcriptional regulation of adipocyte lipolysis by IRF2BP2

Y Chen, L Liu, R Calhoun, L Cheng, D Merrick… - Science …, 2025 - science.org
Adipocyte lipolysis controls systemic energy levels and metabolic homeostasis. Lipolysis is
regulated by posttranslational modifications of key lipolytic enzymes. However, less is …

Immunomodulatory mechanism of acyclic nucleoside phosphates in treatment of hepatitis B virus infection

K Murata, S Tsukuda, F Suizu, A Kimura… - Hepatology, 2020 - journals.lww.com
Conclusions Among NUCs, only ANPs have an additional pharmacological effect
modulating LPS‐mediated cytokine production, which is expected to produce favorable …

Loss of IRF2BPL impairs neuronal maintenance through excess Wnt signaling

PC Marcogliese, D Dutta, SS Ray, NDP Dang… - Science …, 2022 - science.org
De novo truncations in Interferon Regulatory Factor 2 Binding Protein Like (IRF2BPL) lead to
severe childhood-onset neurodegenerative disorders. To determine how loss of IRF2BPL …

p38MAPKα stromal reprogramming sensitizes metastatic breast cancer to immunotherapy

DV Faget, X Luo, MJ Inkman, Q Ren, X Su, K Ding… - Cancer discovery, 2023 - AACR
Metastatic breast cancer is an intractable disease that responds poorly to immunotherapy.
We show that p38MAPKα inhibition (p38i) limits tumor growth by reprogramming the …

Molecular profiling reveals features of clinical immunity and immunosuppression in asymptomatic P. falciparum malaria

SI Studniberg, LJ Ioannidis, RAS Utami… - Molecular Systems …, 2022 - embopress.org
Clinical immunity to P. falciparum malaria is non‐sterilizing, with adults often experiencing
asymptomatic infection. Historically, asymptomatic malaria has been viewed as beneficial …

Resveratrol ameliorates atherosclerosis induced by high-fat diet and LPS in ApoE−/− mice and inhibits the activation of CD4+ T cells

L Zhou, J Long, Y Sun, W Chen, R Qiu, D Yuan - Nutrition & Metabolism, 2020 - Springer
Background Atherosclerosis (AS), which characterized with the accumulation of lipids on the
vessel wall, is the pathological basis of many cardiovascular diseases (CVD) and seriously …