To study virus–host protein interactions, knowledge about viral and host protein
architectures and repertoires, their particular evolutionary mechanisms, and information on …

Infectious diseases are still among the major and prevalent health problems, mostly
because of the drug resistance of novel variants of pathogens. Molecular interactions …

The virus interacts with its hosts by developing protein-protein interactions. Most viruses
employ protein interactions to imitate the host protein: A viral protein with the same amino …

The current therapeutic arsenal against viral infections remains limited, with often poor
efficacy and incomplete coverage, and appears inadequate to face the emergence of drug …

Abstract Domain–motif interactions (DMIs) represent transient bonds formed when a Short
Linear Motif (SLiM) engages a globular domain via a compact contact interface …

In recent years, massive attention has been attracted to the development and application of
machine learning (ML) in the field of infectious diseases, not only serving as a catalyst for …

Rich data bearing on the structural and evolutionary principles of protein–protein
interactions are paving the way to a better understanding of the regulation of function in the …

Background The difficulty in distinguishing infection by Zika virus (ZIKV) from other
flaviviruses is a global health concern, particularly given the high risk of neurologic …

Microbes, commensals, and pathogens, control the numerous functions in the host cells.
They can alter host signaling and modulate immune surveillance by interacting with the host …

Background Grass carp hemorrhagic disease, caused by grass carp reovirus (GCRV), is the
most fatal causative agent in grass carp aquaculture. Protein-protein interactions between …