Objective Metabolic signatures have emerged as valuable signaling molecules in the
biochemical process of type 2 diabetes (T2D). To summarize and identify metabolic …

Background Metabolomics is a promising tool of cardiovascular biomarker discovery. We
systematically reviewed the literature on comprehensive metabolomic profiling in …

Diverse forms of unwanted signal variations in mass spectrometry-based metabolomics data
adversely affect the accuracies of metabolic profiling. A variety of normalization methods …

The separation, identification and quantification of constituents in complex plant extracts
always has been, and most likely will be, a challenging task. Nevertheless, today a …

Amino acids are present in a variety of matrices from biological fluids to plant and animal
tissues. We discuss options for amino acid extraction, sample clean-up and protein …

A targeted reversed-phase gradient UPLC-MS/MS assay has been developed for the
quantification/monitoring of 66 amino acids and amino-containing compounds in human …

Improving the quantitative performance of mass spectrometry (MS)-based metabolomics is
the key to its successful application in a broad range of research questions. Like other …

Free fatty acids (FFAs) are vitally important components of lipids that modulate biological
metabolism in various ways. Although the molecular structures are simple, the analysis of …

A novel liquid organic fertilizer (LOF) was made from spent mushroom substrate (SMS) and
then the resultant fertilizer (SMS-LOF) was applied on Pak-choi in this study. Results …

Amino acids are important metabolites for tissue metabolism, growth, maintenance, and
repair, which are basic life necessities. Therefore, summarizing analytical methods for amino …