Most glomerulonephritides, even the more common types, are rare diseases. They are
nevertheless important since they frequently affect young people, often cannot be cured, and …

Genetic studies of hereditary forms of nephrotic syndrome have identified several proteins
that are involved in regulating the permselective properties of the glomerular filtration …

Recurrence of focal segmental glomerulosclerosis (rFSGS) after kidney transplantation is a
cause of accelerated graft loss. To evaluate pathogenic antibodies (Abs) in rFSGS, we …

Excess levels of protein in urine (proteinuria) is a hallmark of kidney disease that typically
occurs in conjunction with diabetes, hypertension, gene mutations, toxins or infections but …

The term idiopathic nephrotic syndrome (iNS) traditionally covers minimal change disease
and primary focal segmental glomerulosclerosis (FSGS), now thought to be separate …

It has been suggested that soluble urokinase receptor (suPAR) is a causative circulating
factor for and a biomarker of focal and segmental glomerulosclerosis (FSGS). Here we …

Inflammation is a key player in the development of an increasing amount of diseases. The
soluble urokinase plasminogen activator receptor (suPAR) is a highly flexible molecule with …

Primary focal segmental glomerulosclerosis (FSGS) is a major cause of the nephrotic
syndrome and often leads to end‐stage renal disease. This review focuses on circulating …

Background: Inflammation is a common feature of many kidney diseases. The implicated
inflammatory mediators and their underlying molecular mechanisms however are often not …

Soluble urokinase plasminogen activator receptor (suPAR) is an immune-derived circulating
signaling molecule that has been implicated in chronic kidney disease, such as focal …