Glioblastoma (GBM) is a highly lethal cancer that is universally refractory to the standard
multimodal therapies of surgical resection, radiation, and chemotherapy treatment …

Background Meningioma incidence increases significantly with age. In the expanding
elderly population, we lack complete understanding of population-based trends in …

Background Glioblastoma (GBM) is the most lethal and aggressive malignant primary brain
tumor in adults. After surgical resection of the tumor, the patient typically should be subjected …

High-grade astrocytoma of WHO grade 4 termed glioblastoma multiforme (GBM) is a
common human brain tumor with poor patient outcome. Astrocytoma demonstrates two …

High-grade gliomas (HGG) afflict both children and adults and respond poorly to current
therapies. Epigenetic regulators have a role in gliomagenesis, but a broad, functional …

Metastasis is a serious risk that may occur during the treatment of hepatocellular carcinoma
(HCC), preventing many patients from being surgical candidates and contributing to poor …

Background Glioblastoma is the most common and deadliest primary brain tumor for
humans. Despite many efforts toward the improvement of therapeutic methods, prognosis is …

Current treatment against glioblastoma consists of surgical resection followed by
temozolomide, with or without combined radiotherapy. Glioblastoma frequently acquires …

Gliomas are the most commonly occurring malignant brain tumor characterized by an
immunosuppressive microenvironment accompanied by profound epigenetic changes, thus …

Purpose Gliomas, characterized by aggressiveness and invasiveness, remain incurable
after conventional therapies. The molecular mechanisms driving the progression and …