Pediatric AKI has become a significant health concern due to its rising incidence and
association with adverse outcomes. Because of the limitations of serum creatinine, ongoing …

Proteinuria is a hallmark of kidney disease. Therefore, measurement of urine protein content
plays a central role in any diagnostic work-up for kidney disease. In many cases, proteinuria …

Prenatal alcohol exposure (PAE) can result in cognitive and behavioral disabilities and
growth deficits. Because alcohol-related neurobehavioral deficits may occur in the absence …

Results Cumulative incidence of AKI during the first 2 postnatal weeks was 28 of 113 (25%).
Infants with AKI had higher maximum levels of urine cystatin C, neutrophil gelatinase …

Background Research on acute kidney injury (AKI) has focused on identifying early
biomarkers. However, whether AKI could be diagnosed in the absence of the classic signs of …

Congenital obstructive nephropathy (CON) is the leading cause of chronic kidney disease
(CKD) in children. Anomalies of the urinary tract are often associated with abnormal …

Background: Acute kidney injury (AKI) in the neonatal intensive care setting is multifactorial
and is associated with significant morbidity and mortality. This study evaluates the utility of …

Acute kidney injury (AKI) is increasingly recognized as a common problem in children
undergoing cardiac surgery, with well documented increases in morbidity and mortality in …

OBJECTIVE: Novel biomarkers, such as kidney injury molecule-1 (KIM-1), cystatin, and
neutrophil gelatinase-associated lipocalin (NGAL) were shown to predict acute kidney injury …

Background Urinary biomarkers may be indicators of acute kidney injury (AKI), although little
is known of their developmental characteristics in healthy neonates across a full range of …