Supramolecular chemical biology: designed receptors and dynamic chemical systems

I Alfonso - Chemical Communications, 2024 - pubs.rsc.org
Supramolecular chemistry focuses on the study of species joined by non-covalent
interactions, and therefore on dynamic and relatively ill-defined structures. Despite being a …

Biomimetic Charge‐Neutral Anion Receptors for Reversible Binding and Release of Highly Hydrated Phosphate in Water

M He, Y Yao, Z Yang, B Li, J Wang, Y Wang… - Angewandte …, 2024 - Wiley Online Library
Control of phosphate capture and release is vital in environmental, biological, and
pharmaceutical contexts. However, the binding of trivalent phosphate (PO43−) in water is …

Synthetic transporters for oxoanions

K Norvaisa, A Torres-Huerta, H Valkenier - Current opinion in chemical …, 2024 - Elsevier
This brief review highlights recent advances in the transport of oxoanions using synthetic
carriers, focusing on both progress and ongoing challenges in the field. The difficulty of …

pH-Dependent phosphate separation using a tripodal hexaurea receptor

ZY Sun, SQ Chen, L Liang, W Zhao, XJ Yang… - Chemical …, 2023 - pubs.rsc.org
We demonstrate that a tripodal hexaurea receptor can selectively bind PO43− anions via 12
hydrogen bonds with up to 3.8× 106 M− 1 binding affinity in DMSO, which is 38-fold stronger …

Probing and evaluating transmembrane chloride ion transport in double walled trifluorophenyl/phthalimide extended calix [4] pyrrole-based supramolecular receptors

IA Rather, M Ahmad, P Talukdar, R Ali - Journal of Materials Chemistry …, 2024 - pubs.rsc.org
Therapeutic applications have sparked increased interest in the use of synthetic anion
receptors for ion transport across lipid membranes. In this context, the construction of …

Pnictogen-Bonding Catalysis Compared with Ion Transport in Lipid Bilayer Membranes: Entering the Goldilocks Inverted Region

QX Zhang, G Renno, JJ Nué-Martinez… - CCS …, 2024 - chinesechemsoc.org
Antimony-centered pnictogen bonds at the stibine level have provided access to good
catalysis in solution and outstanding ion transport and catalysis in lipid bilayer membranes …

[HTML][HTML] Synthetic ion channels in biomembranes

A Kohata, K Kinbara - Current Opinion in Chemical Biology, 2025 - Elsevier
Ion transport across cell membranes is crucial in maintaining ion homeostasis in cells.
Synthetic molecules that can mimic the functions of natural ion channel proteins would …

Synthesis and supramolecular properties of all-cis-2, 4, 6-trifluorocyclohexane-1, 3, 5-triol

SV Haridas, M von Delius - Chemical Communications, 2024 - pubs.rsc.org
Synthesis and supramolecular properties of all- cis -2,4,6-trifluorocyclohexane-1,3,5-triol -
Chemical Communications (RSC Publishing) DOI:10.1039/D3CC05510H Royal Society of …

Artificial transmembrane channel constructed from shape-persistent covalent organic molecular cages capable of ion and small molecule transport

B Bishop, S Huang, H Chen, H Yu, H Long… - Chinese Chemical …, 2024 - Elsevier
Shape-persistent arylene ethynylene molecular cages have been investigated as
transmembrane channels for ions and small molecules. The molecular cages were obtained …

A Semiflexible Tetrahydrazone Macrocycle for Binding of Pyrophosphate and Smaller Anions

L Halgreen, A Torres-Huerta, K Norvaisa… - The Journal of …, 2024 - ACS Publications
Macrocyclization has proven to be a useful design strategy in the development of efficient
anion receptors. In addition to the ring size, the overall preorganization due to structural …