Effect of alcohol use on the adolescent brain and behavior

B Lees, LR Meredith, AE Kirkland, BE Bryant… - Pharmacology …, 2020 - Elsevier
Adolescence is a particularly vulnerable neurodevelopmental period marked by high rates
of engagement with risky alcohol use. This review summarizes the cognitive and neural …

Effects of adolescent alcohol consumption on the brain and behaviour

LP Spear - Nature Reviews Neuroscience, 2018 - nature.com
Per occasion, alcohol consumption is higher in adolescents than in adults in both humans
and laboratory animals, with changes in the adolescent brain probably contributing to this …

Adolescent drug exposure: A review of evidence for the development of persistent changes in brain function

H Salmanzadeh, SM Ahmadi-Soleimani… - Brain research …, 2020 - Elsevier
Over the past decade, many studies have indicated that adolescence is a critical period of
brain development and maturation. The refinement and maturation of the central nervous …

Mechanisms of persistent neurobiological changes following adolescent alcohol exposure: NADIA consortium findings

FT Crews, DL Robinson, LJ Chandler… - Alcoholism: clinical …, 2019 - Wiley Online Library
The Neurobiology of Adolescent Drinking in Adulthood (NADIA) Consortium has focused on
the impact of adolescent binge drinking on brain development, particularly on effects that …

Consequences of adolescent drug use

MR Steinfeld, MM Torregrossa - Translational psychiatry, 2023 - nature.com
Substance use in adolescence is a known risk factor for the development of neuropsychiatric
and substance use disorders in adulthood. This is in part due to the fact that critical aspects …

The role of the orbitofrontal cortex in alcohol use, abuse, and dependence

DE Moorman - Progress in Neuro-Psychopharmacology and …, 2018 - Elsevier
One of the major functions of the orbitofrontal cortex (OFC) is to promote flexible motivated
behavior. It is no surprise, therefore, that recent work has demonstrated a prominent impact …

Automatic skull stripping of rat and mouse brain MRI data using U-Net

LM Hsu, S Wang, P Ranadive, W Ban… - Frontiers in …, 2020 - frontiersin.org
Accurate removal of magnetic resonance imaging (MRI) signal outside the brain, aka, skull
stripping, is a key step in the brain image pre-processing pipelines. In rodents, this is mostly …

Neuroimaging in alcohol use disorder: From mouse to man

M Fritz, AM Klawonn, NM Zahr - Journal of neuroscience …, 2022 - Wiley Online Library
This article provides an overview of recent advances in understanding the effects of alcohol
use disorders (AUD) on the brain from the perspective of magnetic resonance imaging (MRI) …

Aging with alcohol-related brain damage: Critical brain circuits associated with cognitive dysfunction

PT Nunes, BT Kipp, NL Reitz, LM Savage - International review of …, 2019 - Elsevier
Alcoholism is associated with brain damage and impaired cognitive functioning. The relative
contributions of different etiological factors, such as alcohol, thiamine deficiency and age …

[HTML][HTML] Adolescent alcohol exposure reduces dopamine 1 receptor modulation of prelimbic neurons projecting to the nucleus accumbens and basolateral amygdala

JD Obray, JD Landin, DT Vaughan, MD Scofield… - Addiction …, 2022 - Elsevier
Binge drinking during adolescence is highly prevalent despite increasing evidence of its
long-term impact on behaviors associated with modulation of behavioral flexibility by the …