Inflammatory and microbiota-related regulation of the intestinal epithelial barrier

G Barbara, MR Barbaro, D Fuschi, M Palombo… - Frontiers in …, 2021 - frontiersin.org
The intestinal epithelial barrier (IEB) is one of the largest interfaces between the
environment and the internal milieu of the body. It is essential to limit the passage of harmful …

[HTML][HTML] Sex-gender differences in irritable bowel syndrome

YS Kim, N Kim - Journal of neurogastroenterology and motility, 2018 - ncbi.nlm.nih.gov
Because of the sex-gender differences that are shown in a diversity of physiological and
psychological factors, it can be speculated that the clinical presentation of symptoms as well …

Probiotic Bifidobacterium longum NCC3001 reduces depression scores and alters brain activity: a pilot study in patients with irritable bowel syndrome

MI Pinto-Sanchez, GB Hall, K Ghajar, A Nardelli… - Gastroenterology, 2017 - Elsevier
Background & Aims Probiotics can reduce symptoms of irritable bowel syndrome (IBS), but
little is known about their effects on psychiatric comorbidities. We performed a prospective …

American College of Gastroenterology monograph on management of irritable bowel syndrome

AC Ford, P Moayyedi, WD Chey, LA Harris… - Official journal of the …, 2018 - journals.lww.com
Irritable bowel syndrome (IBS) is the most prevalent of the functional gastrointestinal
disorders (FGIDs). Current estimates are that IBS affects up to 10–12% of adults in North …

The mucosal immune system: master regulator of bidirectional gut–brain communications

N Powell, MM Walker, NJ Talley - Nature reviews Gastroenterology & …, 2017 - nature.com
Communication between the brain and gut is not one-way, but a bidirectional highway
whereby reciprocal signals between the two organ systems are exchanged to coordinate …

Immune activation in irritable bowel syndrome: what is the evidence?

J Aguilera-Lizarraga, H Hussein… - Nature Reviews …, 2022 - nature.com
Irritable bowel syndrome (IBS) is a chronic functional gastrointestinal disorder that is
characterized by abdominal pain and an altered defecation pattern. It affects between 5 and …

Effects of varying dietary content of fermentable short‐chain carbohydrates on symptoms, fecal microenvironment, and cytokine profiles in patients with irritable bowel …

TN Hustoft, T Hausken, SO Ystad… - …, 2017 - Wiley Online Library
Background A diet low in fermentable oligosaccharides, disaccharides, monosaccharides,
and polyols (FODMAP s) is increasingly recommended for patients with irritable bowel …

Understanding neuroimmune interactions in disorders of gut–brain interaction: from functional to immune-mediated disorders

T Vanuytsel, P Bercik, G Boeckxstaens - Gut, 2023 - gut.bmj.com
Functional gastrointestinal disorders—recently renamed into disorders of gut–brain
interaction—such as irritable bowel syndrome and functional dyspepsia are highly prevalent …

The impact of gut microbiota on brain and behaviour: implications for psychiatry

TG Dinan, JF Cryan - Current Opinion in Clinical Nutrition & …, 2015 - journals.lww.com
The impact of gut microbiota on brain and behaviour: implica... : Current Opinion in Clinical
Nutrition & Metabolic Care The impact of gut microbiota on brain and behaviour: implications …

Towards a systems view of IBS

EA Mayer, JS Labus, K Tillisch, SW Cole… - Nature Reviews …, 2015 - nature.com
Despite an extensive body of reported information about peripheral and central mechanisms
involved in the pathophysiology of IBS symptoms, no comprehensive disease model has …