CN Bodnar, KN Roberts, EK Higgins… - Journal of …, 2019 - liebertpub.com
Mild TBI (mTBI) is a significant health concern. Animal models of mTBI are essential for understanding mechanisms, and pathological outcomes, as well as to test therapeutic …
JR Moffett, B Ross, P Arun, CN Madhavarao… - Progress in …, 2007 - Elsevier
The brain is unique among organs in many respects, including its mechanisms of lipid synthesis and energy production. The nervous system-specific metabolite N-acetylaspartate …
G Barkhoudarian, DA Hovda… - Clinics in sports …, 2011 - sportsmed.theclinics.com
Concussion (or mild traumatic brain injury, mTBI) is a biomechanically induced neurological injury, resulting in an alteration of mental status, such as confusion or amnesia, which may …
G Barkhoudarian, DA Hovda… - Physical Medicine and …, 2016 - pmr.theclinics.com
Concussion (mild traumatic brain injury [TBI]), particularly with organized sports, has come to the forefront of popular culture. Affecting about 1.6 million to 3.8 million athletes a year, its …
R Vagnozzi, S Signoretti, L Cristofori, F Alessandrini… - Brain, 2010 - academic.oup.com
Concussive head injury opens a temporary window of brain vulnerability due to the impairment of cellular energetic metabolism. As experimentally demonstrated, a second mild …
R Vagnozzi, S Signoretti, B Tavazzi, R Floris… - …, 2008 - journals.lww.com
OBJECTIVE: In the present study, the occurrence of the temporal window of brain vulnerability was evaluated in concussed athletes by measuring N-acetylaspartate (NAA) …
S Signoretti, G Lazzarino, B Tavazzi, R Vagnozzi - Pm&r, 2011 - Elsevier
Concussion is defined as a biomechanically induced brain injury characterized by the absence of gross anatomic lesions. Early and late clinical symptoms, including impairments …
R Vagnozzi, B Tavazzi, S Signoretti, AM Amorini… - …, 2007 - journals.lww.com
OBJECTIVE In the present study, we investigate the existence of a temporal window of brain vulnerability in rats undergoing repeat mild traumatic brain injury (mTBI) delivered at …
JR Moffett, P Arun, PS Ariyannur… - Frontiers in …, 2013 - frontiersin.org
N-Acetylaspartate (NAA) is employed as a non-invasive marker for neuronal health using proton magnetic resonance spectroscopy (MRS). This utility is afforded by the fact that NAA …