Mesenchymal stem cell-based therapies are promising tools for bone tissue regeneration.
However, tracking cells and maintaining them in the site of injury is difficult. A potential …

Bone generally displays a high intrinsic capacity to regenerate. Nonetheless, large osseous
defects sometimes fail to heal. The treatment of such large segmental defects still represents …

Background The periosteum stem cells (PSCs) plays a critical role in bone regeneration and
defect reconstruction. Insertion of polymethyl methacrylate (PMMA) bone cement can form …

A large bone defect is defined as a defect that exceeds the regenerative capacity of the
bone. Nowadays, autologous bone grafting is still the gold standard treatment. In this study …

Bioprinting can be considered as a progression of the classical tissue engineering
approach, in which cells are randomly seeded into scaffolds. Bioprinting offers the …

Regenerative cell-based implants using periosteum-derived stem cells were developed for
the treatment of large 3 cm fresh and 4.5 centimeter biological compromised bone gaps in a …

Reconstruction of bone defects and maintaining the continuity of the mandible is still a
challenge in the maxillofacial surgery. Nowadays, the biomedical research within bone …

Background: Articular cartilage repair has been a challenge in orthopedic practice due to the
limited self-regenerative capability. Optimal treatment method for cartilage defects has not …

ABSTRACT Background and Objective Porcine translational models have become the gold-
standard translational tool to study the effects of major injury and hemorrhagic shock …

Bone generally displays a high intrinsic capacity to regenerate. Nonetheless, large osseous
defects sometimes fail to heal. The treatment of such large segmental defects still represents …