Hepatic stellate cells (HSCs) comprise a minor cell population in the liver but serve
numerous critical functions in the normal liver and in response to injury. HSCs are primarily …

Much evidence has accumulated in the literature over the last fifteen years that indicates
vitamin A has a role in metabolic disease prevention and causation. This literature proposes …

Animals are biological transformers of dietary matter and energy to produce high-quality
foods and wools for human consumption and use. Mammals, birds, fish, and shrimp require …

Retinol binding protein 4 (RBP4) is a member of the lipocalin family and the major transport
protein of the hydrophobic molecule retinol, also known as vitamin A, in the circulation …

Liver fibrosis is a regenerative process that occurs after injury. It is characterized by the
deposition of connective tissue by specialized fibroblasts and concomitant proliferative …

Liver fibrosis represents a health problem with significant morbidity and mortality that affects
100 million people worldwide. It is a final pathway to several chronic liver diseases and is …

Retinoids are required for maintaining many essential physiological processes in the body,
including normal growth and development, normal vision, a healthy immune system, normal …

By definition, a vitamin is a substance that must be obtained regularly from the diet. Vitamin
A must be acquired from the diet, but unlike most vitamins, it can also be stored within the …

Abstract Cellular binding-proteins (BP), including CRBP1, CRBP2, CRABP1, CRABP2, and
FABP5, shepherd the poorly aqueous soluble retinoids during uptake, metabolism and …

Retinoids (ie, vitamin A, all-trans retinoic acid, and related signaling molecules) induce the
differentiation of various types of stem cells. Nuclear retinoic acid receptors mediate most but …