Epithelial mesenchymal transition (EMT), the adoption by epithelial cells of a mesenchymal-
like phenotype, is a process co-opted by carcinoma cells in order to initiate invasion and …

Oral squamous cell carcinoma (OSCC) is characterized by genomic and epigenomic
alterations. However, the mechanisms underlying oral squamous cell carcinoma …

To date, there is only up to 2% of protein-coding genes that are stably transcribed, whereas
the vast majority are non-coding RNAs (ncRNAs). These ncRNAs, also known as non …

Cancerous tumours contain a rare subset of cells with stem‐like properties that are termed
cancer stem cells (CSCs). CSCs are defined by their ability to divide both symmetrically and …

DNA double-strand breaks (DSBs) are deleterious lesions that are generated in response to
ionizing radiation or replication fork collapse that can lead to genomic instability and cancer …

Amongst the various gynecological malignancies affecting female health globally, ovarian
cancer is one of the predominant and lethal among all. The identification and functional …

Non-coding RNAs (ncRNAs) are involved in the regulation of cell metabolism and neoplastic
transformation. Recent studies have tried to clarify the significance of these information …

The cancer stem-like cell (CSC) hypothesis postulates that a small population of cells in a
cancer has self-renewal and clonal tumor initiation properties. These cells are responsible …

Background Cancer is associated with various genetic and environmental risk factors.
Beside the mutations or aberrant expression of protein-coding genes, the genetic …

DNA double strand breaks (DSBs) are abrasions caused in both strands of the DNA duplex
following exposure to both exogenous and endogenous conditions. Such abrasions have …