Improving intestinal inflammaging to delay aging? A new perspective

L Zhang, J Yan, C Zhang, S Feng, Z Zhan, Y Bao… - Mechanisms of Ageing …, 2023 - Elsevier
Greying population is becoming an increasingly critical issue for social development. In
advanced aging context, organismal multiple tissues and organs experience a progressive …

Silibinin alleviates intestinal inflammation via inhibiting JNK signaling in Drosophila

L Yan, J Zhou, L Yuan, J Ye, X Zhao, G Ren… - Frontiers in …, 2023 - frontiersin.org
Inflammatory bowel diseases (IBDs) are characterized by chronic relapsing intestinal
inflammation that causes digestive system dysfunction. For years, researchers have been …

The Protective Effects of Carrageenan Oligosaccharides on Intestinal Oxidative Stress Damage of Female Drosophila melanogaster

K Yang, Q Li, G Zhang, C Ma, X Dai - Antioxidants, 2021 - mdpi.com
Carrageenan oligosaccharides (COS) have been reported to possess excellent antioxidant
activities, but the underlying mechanism remains poorly understood. In this study, H2O2 was …

Vitamin B12 ameliorates gut epithelial injury via modulating the HIF-1 pathway and gut microbiota

C Feng, J Yan, T Luo, H Zhang, H Zhang… - Cellular and Molecular …, 2024 - Springer
Inflammatory bowel diseases (IBDs) are immune chronic diseases characterized by
recurrent episodes, resulting in continuous intestinal barrier damage and intestinal …

Drosophila as a model to study autophagy in neurodegenerative diseases and digestive tract

FY Tzou, JK Wen, JY Yeh, SY Huang, GC Chen… - IUBMB …, 2022 - Wiley Online Library
Autophagy regulates cellular homeostasis by degrading and recycling cytosolic components
and damaged organelles. Disruption of autophagic flux has been shown to induce or …

[PDF][PDF] 加齢に伴う腸管機能低下と腸内細菌叢変化の機構解析

矢野環 - 上原記念生命科学財団研究報告集, 2023 - ueharazaidan.or.jp
腸管内には多様な種類の常在細菌が存在し, 食餌成分の消化, 分解, 腸管免疫系との相互作用など
, 宿主生理機能に大きく寄与している. 腸内常在菌叢は食餌や宿主の免疫, 疾患などにより変動し …