The emerging roles of human leukocyte antigen-F in immune modulation and viral infection

A Lin, WH Yan - Frontiers in immunology, 2019 - frontiersin.org
Human leukocyte antigens (HLAs) play various critical roles in both innate and adaptive
immunity through processes such as presenting antigens to T cells and serving as ligands …

HLA class I molecules as immune checkpoints for NK cell alloreactivity and anti-viral immunity in kidney transplantation

B Duygu, TI Olieslagers, M Groeneweg… - Frontiers in …, 2021 - frontiersin.org
Natural killer (NK) cells are innate lymphocytes that can kill diseased-or virally-infected cells,
mediate antibody dependent cytotoxicity and produce type I immune-associated cytokines …

HLA-G genetic diversity and evolutive aspects in worldwide populations

EC Castelli, BS de Almeida, YCN Muniz, NSB Silva… - Scientific reports, 2021 - nature.com
HLA-G is a promiscuous immune checkpoint molecule. The HLA-G gene presents
substantial nucleotide variability in its regulatory regions. However, it encodes a limited …

HLAIb worldwide genetic diversity: New HLA-H alleles and haplotype structure description

J Paganini, L Abi-Rached, P Gouret, P Pontarotti… - Molecular …, 2019 - Elsevier
The classical HLA class I genes (HLA Ia) were extensively studied because of their
implication in clinical fields and anthropology. Less is known about worldwide genetic …

[HTML][HTML] HLA-G and single nucleotide polymorphism (SNP) associations with cancer in African populations: Implications in personal medicine

IC Adolf, A Almars, N Dharsee, T Mselle, G Akan… - Genes & …, 2022 - Elsevier
The immune system plays an important role in protecting the body against malignancy.
During cancer immunoediting, the immune system can recognize and keep checking the …

Extended loci histocompatibility matching in HSCT—Going beyond classical HLA

C Neuchel, D Fürst, C Tsamadou… - International Journal …, 2021 - Wiley Online Library
Unrelated haematopoietic stem cell transplantation (HSCT) has evolved from an
experimental protocol to a potentially curative first‐line treatment in a variety of haematologic …

HLA-G polymorphisms are associated with non-segmental vitiligo among Brazilians

L Veiga-Castelli, ML de Oliveira, A Pereira, G Debortoli… - Biomolecules, 2019 - mdpi.com
(1) Background: Vitiligo is characterized by white patches on the skin caused by loss of
melanocyte activity or the absence of these cells. The available treatments minimize the …

HLA-G 3'UTR haplotype frequencies in highland and lowland South Native American populations

VC Jacovas, RT Michita, R Bisso-Machado, G Reales… - Human Immunology, 2022 - Elsevier
Abstract Human Leukocyte Antigen (HLA)-G participates in several biological processes,
including reproduction, vascular remodeling, immune tolerance, and hypoxia response. HLA …

Correlation of human leukocyte antigen-E genomic polymorphism with leukemia and functional study of human leukocyte antigen-E different type promoters

YP Xu, LY Sun, SX Wang, WX Hong - DNA and Cell Biology, 2022 - liebertpub.com
Human leukocyte antigen (HLA)-E is one of the least polymorphic nonclassical major
histocompatibility complex (MHC) I genes; its nucleotide variability can affect immune …

HLA-E gene polymorphisms in chronic hepatitis C: Impact on HLA-E liver expression and disease severity

RC Araujo, BC Bertol, FC Dias, G Debortoli… - Human immunology, 2021 - Elsevier
Hepatitis C virus usually produces chronic infection and liver damage. Considering that: i)
the human leukocyte antigen-E (HLA-E) molecule may modulate the immune response, and …