Bacillus subtilis EA-CB0575 genome reveals clues for plant growth promotion and potential for sustainable agriculture

ND Franco-Sierra, LF Posada, G Santa-María… - Functional & integrative …, 2020 - Springer
Bacillus subtilis is a remarkably diverse bacterial species that displays many ecological
functions. Given its genomic diversity, the strain Bacillus subtilis EA-CB0575, isolated from …

Identification of potential drug targets by subtractive genome analysis of Escherichia coli O157:H7: an in silico approach

SI Mondal, S Ferdous, NA Jewel, A Akter… - … and applications in …, 2015 - Taylor & Francis
Bacterial enteric infections resulting in diarrhea, dysentery, or enteric fever constitute a huge
public health problem, with more than a billion episodes of disease annually in developing …

Genome-wide core proteome analysis of Brucella melitensis strains for potential drug target prediction

N Rahman, M Shah, I Muhammad… - Mini Reviews in …, 2021 - ingentaconnect.com
Introduction: Brucella melitensis is a facultative intracellular bacterial pathogen that causes
abortion in goats and sheep and Malta fever in humans. In humans, chronic infection occurs …

[HTML][HTML] Core proteome mediated therapeutic target mining and multi-epitope vaccine design for Helicobacter pylori

N Rahman, A Ajmal, F Ali, L Rastrelli - Genomics, 2020 - Elsevier
Helicobacter pylori is a Gram-negative spiral-shaped bacterium that infects half of the
human population worldwide and causes chronic inflammation. In the present study, we …

Targeting shikimate pathway: In silico analysis of phosphoenolpyruvate derivatives as inhibitors of EPSP synthase and DAHP synthase

MD de Oliveira, JO Araujo, JMP Galúcio… - Journal of Molecular …, 2020 - Elsevier
The shikimate pathway consists of seven enzymatic steps involved in the conversion of
erythrose-4-phosphate and phosphoenolpyruvate to chorismate and also responsible to the …

[HTML][HTML] Computational identification of putative common genomic drug and vaccine targets in Mycoplasma genitalium

WG Nogueira, AK Jaiswal, S Tiwari, RTJ Ramos… - Genomics, 2021 - Elsevier
Mycoplasma genitalium is an obligate intracellular bacterium that is responsible for several
sexually transmitted infections, including non-gonococcal urethritis in men and several …

From drugs to targets: Reverse engineering the virtual screening process on a proteomic scale

G Schottlender, JM Prieto, MC Palumbo… - Frontiers in Drug …, 2022 - frontiersin.org
Phenotypic screening is a powerful technique that allowed the discovery of antimicrobials to
fight infectious diseases considered deadly less than a century ago. In high throughput …

Reverse vaccinology and subtractive genomics-based putative vaccine targets identification for Burkholderia pseudomallei Bp1651

Z Nazir, SG Afridi, M Shah, S Shams, A Khan - Microbial pathogenesis, 2018 - Elsevier
The Burkholderia pseudomallei is a unique bio-threat and causative agent of melioidosis.
The B. pseudomallei Bp1651 strain has been isolated from a chronic cystic fibrosis patient …

Identification of putative drug targets in Vancomycin-resistant Staphylococcus aureus (VRSA) using computer aided protein data analysis

MA Hasan, MA Khan, T Sharmin, MHH Mazumder… - Gene, 2016 - Elsevier
Vancomycin-resistant Staphylococcus aureus (VRSA) is a Gram-positive, facultative aerobic
bacterium which is evolved from the extensive exposure of Vancomycin to Methicillin …

Finding Potential Therapeutic Targets against Shigella flexneri through Proteome Exploration

MU Hossain, MA Khan, A Hashem, MM Islam… - Frontiers in …, 2016 - frontiersin.org
Background: Shigella flexneri is a gram negative bacteria that causes the infectious disease
“shigellosis.” S. flexneri is responsible for developing diarrhea, fever, and stomach cramps in …