Stem cells have certain unique characteristics, which include longevity, high capacity of self-
renewal with a long cell cycle time and a short S-phase duration, increased potential for …

Defects in renewal and repair of ocular surface as a result of limbal stem cell deficiency are
now known to cause varying ocular surface morbidity including persistent photophobia …

Contact lens-related complications are common, affecting around one third of wearers,
although most are mild and easily managed. Contact lenses have well-defined anatomical …

This study describes a novel surgical technique of limbal transplantation, which combines
the benefits of existing techniques while avoiding their difficulties. Six patients with unilateral …

Purpose: In recent decades, the medical and surgical treatment of limbal stem cell deficiency
(LSCD) has evolved significantly through the incorporation of innovative pharmacological …

This study evaluated proposed molecular markers related to stem cell (SC) properties with
the intention of characterizing a putative SC phenotype in human limbal epithelia. Human …

Simple limbal epithelial transplantation (SLET) is an innovative limbal stem cell
transplantation technique that has gained increasing popularity over the last few years …

Purpose. To bioengineer a corneal surface replacement using ex vivo expanded, cultured
corneal epithelial stem cells seeded on a matrix derived from amniotic membrane and use …

Ex vivo cultured limbal epithelial stem cells have been used successfully to treat corneal
limbal stem cell deficiency. We identified 17 reports of the application of this novel cell …

For 30 years, contact lens research focused on the need for highly oxygen-permeable (Dk)
soft lens materials. High Dk silicone hydrogel contact lenses, made available in 1999, met …